Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL11045330 | 0.83 | TSHR (0.36) | EGLN1MAPT | |
| Butane SCHEMBL11047024 | 0.82 | ACHE (0.36) | GAASMN1; SMN2ALDH1A1MGAMSI | |
| Butane SCHEMBL11024771 | 0.79 | KDM4E (0.33) | KDM4E | |
| SCHEMBL11024760 | 0.71 | EGLN1 (0.52) | EGLN1GAASMN1; SMN2MAPTHTT | |
| SCHEMBL24873009 | 0.71 | EGLN1 (0.61) | EGLN1GAASMN1; SMN2MAPTHTT | |
| SCHEMBL923438 | 0.71 | EGLN1 (0.65) | EGLN1GAASMN1; SMN2MAPTHTT | |
| SCHEMBL12495312 | 0.71 | EGLN1 (0.65) | EGLN1GAASMN1; SMN2MAPTHTT | |
| SCHEMBL13589411 | 0.71 | EGLN1 (0.65) | EGLN1GAASMN1; SMN2MAPTHTT | |
| SCHEMBL11048167 | 0.70 | — | — | |
| SCHEMBL1912783 | 0.70 | EGLN1 (0.59) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063411-B1 | SUBSTITUTED METHANEPHOSHONIC ACID DERIVATIVES, THEIR USE AS HERBICIDES, HERBICIDAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR PREPARING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-06-05 | — | — | EP | disclosed |
| US-4454073-A | HERBICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-06-12 | — | — | US | disclosed |
| EP-0063411-A1 | Substituted methanephoshonic acid derivatives, their use as herbicides, herbicidal compositions containing them, and processes for preparing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-10-27 | — | — | EP | disclosed |