Butane

Butane

SCHEMBL11045330

C=CCOC(=O)C(=O)NCO[PH](=O)O.CCCC

nearest known ligand 0.36

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Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
EGLN1 Q9GZT9 1/20 0.33
MAPT P10636 1/20 0.30
CACNA1B Q00975 1/20 0.30
APBA1 Q02410 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butane SCHEMBL11024656 0.83 EGLN1 (0.49) EGLN1MAPT
Butane SCHEMBL2150699 0.73 TSHR (0.37) TSHR
Butane SCHEMBL11024771 0.73 KDM4E (0.33)
SCHEMBL1723694 0.70 MAPT (0.42) TSHREGLN1MAPTCACNA1BAPBA1
Butane SCHEMBL11047024 0.69 ACHE (0.36) TSHR
SCHEMBL11045332 0.69 TSHR (0.42) TSHREGLN1MAPT
SCHEMBL3657172 0.67 TSHR (0.48) TSHR
Butane SCHEMBL284262 0.66 TSHR (0.60) TSHRMAPTCACNA1BAPBA1
SCHEMBL28064773 0.66 TSHR (0.46) TSHRMAPTCACNA1BAPBA1
SCHEMBL11023916 0.66 EGLN1 (0.37) TSHREGLN1MAPTCACNA1BAPBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4454073-A HERBICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-06-12 US disclosed
EP-0063411-A1 Substituted methanephoshonic acid derivatives, their use as herbicides, herbicidal compositions containing them, and processes for preparing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-10-27 EP disclosed