SCHEMBL11024810

SCHEMBL11024810

CC(=O)O[Sn]CCCC(c1ccc(Cl)cc1)c1ccc(Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 3/20 0.43
CNR1 P21554 2/20 0.40
BRD4 O60885 1/20 0.40
CASR P41180 1/20 0.37
CNR2 P34972 1/20 0.37
GABBR2 O75899 3/20 0.36
GABBR1 Q9UBS5 3/20 0.36
UTS2R Q9UKP6 3/20 0.36
LMNA P02545 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP3A4 P08684 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
NFKB1 P19838 1/20 0.36
DRD3 P35462 1/20 0.36
BLM P54132 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
MEN1 O00255 1/20 0.36
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11024766 0.79 SLC6A3 (0.38) SLC6A3CNR1TSHR
SCHEMBL11025423 0.75 CNR1 (0.41) SLC6A3CNR1CASRCNR2GABBR2
SCHEMBL11278459 0.75 CNR1 (0.41) SLC6A3CNR1CASRCNR2GABBR2
Acetic Acid SCHEMBL11024809 0.72 SLC6A3 (0.45) SLC6A3CNR1BRD4CASRCNR2
SCHEMBL11021374 0.72 SLC6A3 (0.40) SLC6A3CNR1CASRLMNACYP2C9
SCHEMBL11025724 0.70 BRD4 (0.47) SLC6A3CNR1BRD4CNR2GABBR2
SCHEMBL3711770 0.68 SLC6A3 (0.51) SLC6A3CNR1
SCHEMBL7326087 0.68 GABBR2 (0.50) CNR1BRD4CASRCNR2GABBR2
SCHEMBL7333341 0.67 CNR1 (0.41) SLC6A3CNR1LMNACYP2C9NFKB1
SCHEMBL7633113 0.67 CNR1 (0.41) SLC6A3CNR1CASRCNR2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0049643-B1 IMPROVEMENTS IN OR RELATING TO BIS(SUBSTITUTED PHENYL) ALKYLTIN COMPOUNDS M & T Chemicals, Inc. (US) 1985-07-17 EP disclosed
EP-0049643-A2 Improvements in or relating to bis(substituted phenyl) alkyltin compounds M & T Chemicals, Inc. (US) 1982-04-14 EP disclosed
US-4324798-A Fungicidal bis(substituted phenyl)alkyltin compounds M&T CHEMICALS INC. (US) 1982-04-13 US disclosed