Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | CACNA1F | O60840 | 4/20 | 0.54 |
| ▸ | CACNA1D | Q01668 | 4/20 | 0.54 |
| ▸ | CACNA1S | Q13698 | 4/20 | 0.54 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11024931 | 0.95 | ADORA3 (0.60) | ADORA3CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7380696 | 0.83 | ADORA3 (0.62) | ADORA3CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL6951320 | 0.80 | ADORA3 (0.76) | ADORA3CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL28735932 | 0.77 | ADORA3 (0.67) | ADORA3CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL3905675 | 0.76 | ADORA3 (0.83) | ADORA3CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7385215 | 0.75 | ADORA3 (0.57) | ADORA3CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7382516 | 0.74 | ADORA3 (0.50) | ADORA3CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL28735976 | 0.74 | ADORA3 (0.50) | ADORA3CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7380179 | 0.73 | ADORA3 (0.59) | ADORA3CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7266887 | 0.73 | ADORA3 (0.62) | ADORA3CACNA1FCACNA1DCACNA1SCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60064962-A | — | — | None | — | — | JP | disclosed |
| JP-S6064962-A | 2-(BETA-ARYL-BETA-HYDROXYETHYL)DIHYDROPYRIDINE DERIVATIVE AND ITS PREPARATION | NISSAN CHEM IND LTD | 1985-04-13 | — | — | JP | disclosed |