Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCND3 | P30281 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18797548 | 0.85 | SCN9A (0.33) | SCN9AKDM4EGRM5L3MBTL1 | |
| SCHEMBL11023797 | 0.85 | JAK2 (0.38) | SCN9AGRM5MEN1MAPK1KMT2A | |
| SCHEMBL11131247 | 0.85 | BCHE (0.40) | SCN9AGRM5CCNT1CDK1CDK4 | |
| SCHEMBL18328251 | 0.81 | F11 (0.33) | SCN9AKDM4EKCNH2GRM5 | |
| SCHEMBL11134713 | 0.81 | GABRB3 (0.41) | NOTUMKDM4EKCNH2MRGPRX4L3MBTL1 | |
| SCHEMBL11135859 | 0.81 | CYP2A6 (0.40) | CCNT1CDK1CDK4CCNB1CCND1 | |
| SCHEMBL27686519 | 0.81 | BCHE (0.41) | NOTUMKDM4EGRM5L3MBTL1 | |
| SCHEMBL10537587 | 0.79 | NOTUM (0.42) | NOTUMNPSR1GRM5 | |
| SCHEMBL16810229 | 0.78 | NOTUM (0.43) | NOTUMSCN9AKDM4ELMNAALOX12 | |
| SCHEMBL24257824 | 0.76 | NOTUM (0.45) | NOTUMLMNAALOX12NPSR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034945-B1 | N-PHENYLPYRAZOLE DERIVATIVES | MAY & BAKER LIMITED (GB) | 1985-08-07 | — | — | EP | claimed |