Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.55 |
| ▸ | YARS1 | P54577 | 2/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | CTSC | P53634 | 1/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11027926 | 1.00 | SLC7A5 (0.55) | SLC7A5YARS1OPRD1OPRM1OPRK1 | |
| SCHEMBL11026872 | 0.93 | CTSC (0.57) | SLC7A5CTSCALPIPKMPTGS1 | |
| SCHEMBL19750992 | 0.89 | SLC7A5 (0.54) | SLC7A5YARS1OPRD1OPRM1OPRK1 | |
| SCHEMBL11220250 | 0.86 | OPRD1 (0.58) | OPRD1OPRM1OPRK1 | |
| SCHEMBL10626606 | 0.84 | MMP2 (0.57) | SLC7A5CTSCALPIPKMPTGS1 | |
| SCHEMBL3134765 | 0.83 | CTSC (0.56) | SLC7A5OPRD1OPRK1CTSCALPI | |
| Phenylalanyltyrosine SCHEMBL4282059 | 0.82 | MME (0.67) | SLC7A5OPRD1OPRM1OPRK1MME | |
| SCHEMBL8695556 | 0.82 | MME (0.67) | SLC7A5OPRD1OPRM1OPRK1MME | |
| SCHEMBL29511618 | 0.82 | MME (0.67) | SLC7A5OPRD1OPRM1OPRK1MME | |
| Phenylalanyltyrosine SCHEMBL3037096 | 0.82 | MME (0.67) | SLC7A5OPRD1OPRM1OPRK1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0077274-B1 | 3-AMINO-2-HYDROXY-4-PHENYLBUTANOIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1985-08-28 | — | — | EP | claimed |
| US-4474764-A | ANALGESICS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1984-10-02 | — | — | US | claimed |
| EP-0077274-A1 | 3-Amino-2-hydroxy-4-phenylbutanoic acid derivatives and pharmaceutical composition containing the same | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1983-04-20 | — | — | EP | claimed |
| US-4474764-A | ANALGESICS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1984-10-02 | — | — | US | disclosed |