Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439752 | 0.79 | L3MBTL1 (0.49) | L3MBTL1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3518996 | 0.76 | L3MBTL1 (0.41) | L3MBTL1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL11959515 | 0.76 | L3MBTL1 (0.41) | L3MBTL1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL11018422 | 0.76 | L3MBTL1 (0.41) | L3MBTL1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL19292061 | 0.76 | L3MBTL1 (0.41) | L3MBTL1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6571553 | 0.75 | L3MBTL1 (0.40) | L3MBTL1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL438475 | 0.74 | L3MBTL1 (0.48) | L3MBTL1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28543619 | 0.73 | L3MBTL1 (0.40) | L3MBTL1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7100687 | 0.72 | DAO (0.43) | L3MBTL1FDPSALDH1A1DAOHTT | |
| SCHEMBL278529 | 0.71 | L3MBTL1 (0.48) | L3MBTL1LMNAFDPSALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3126335-A1 | N-(1-(HETERO)ARYL-1H-PYRAZOL-4-YL)-(HETERO)ARYLAMIDE DERIVATIVES AND USE THEREOF AS PESTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2017-02-08 | — | — | EP | disclosed |
| WO-2015150300-A1 | N-(1-(HETERO)ARYL-1H-PYRAZOL-4-YL)-(HETERO)ARYLAMIDE DERIVATIVES AND USE THEREOF AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2015-10-08 | — | — | WO | disclosed |
| EP-0205023-A2 | 1-Aryl-4-heterocyclyl-pyrazoles | BAYER AG (DE) | 1986-12-17 | — | — | EP | disclosed |