Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11959515 | 0.87 | L3MBTL1 (0.41) | L3MBTL1TLR8TLR7LMNAPSEN1 | |
| SCHEMBL20940122 | 0.84 | TLR8 (0.39) | L3MBTL1TLR8TLR7LMNAPSEN1 | |
| SCHEMBL439752 | 0.83 | L3MBTL1 (0.49) | L3MBTL1TLR8TLR7LMNAPSEN1 | |
| SCHEMBL796651 | 0.82 | — | — | |
| SCHEMBL45207 | 0.81 | TLR8 (0.44) | L3MBTL1TLR8TLR7LMNAFDPS | |
| Bromide SCHEMBL556174 | 0.81 | TLR8 (0.44) | L3MBTL1TLR8TLR7FDPSNOS1 | |
| Hydrochloric Acid SCHEMBL6736377 | 0.81 | TLR8 (0.44) | L3MBTL1TLR8TLR7FDPSNOS1 | |
| Hydrochloric Acid SCHEMBL557786 | 0.81 | TLR8 (0.44) | L3MBTL1TLR8TLR7FDPSNOS1 | |
| SCHEMBL19292061 | 0.80 | L3MBTL1 (0.41) | L3MBTL1TLR8TLR7LMNAPSEN1 | |
| SCHEMBL11018422 | 0.80 | L3MBTL1 (0.41) | L3MBTL1TLR8TLR7LMNAPSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0813526-B1 | PROCESS FOR PREPARING N-SUBSTITUTED PYRAZOLES | BASF AG (DE) | 2004-02-04 | — | — | EP | disclosed |
| US-5840913-A | CATALYTIC N-ALKYLATION OF A PYRAZOLE BY REACTING WITH AN ALCOHOL; LIQUID PHASE; NON-HETEROGENOUS ACID CATALYSTS | BASF AKTIENGESELLSCHAFT (DE) | 1998-11-24 | — | — | US | disclosed |