Acetic Acid

Acetic Acid

SCHEMBL11025512

CC(=O)O.CC(C)Cc1ccccc1O

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.53
GABRB2 P47870 2/20 0.53
AKR1B1 P15121 1/20 0.53
POLB P06746 1/20 0.46
MAPK1 P28482 1/20 0.46
HSPA5 P11021 1/20 0.45
ELANE P08246 1/20 0.42
CTSG P08311 1/20 0.42
MAPT P10636 1/20 0.41
CRHBP P24387 1/20 0.41
RAB9A P51151 1/20 0.41
CRHR2 Q13324 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
CYP2D6 P10635 1/20 0.41
TSHR P16473 1/20 0.41
HIF1A Q16665 1/20 0.41
IAPP P10997 1/20 0.41
HSP90AA1 P07900 1/20 0.40
HSP90AB1 P08238 1/20 0.40
SLC7A5 Q01650 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108067 0.90 GABRA1 (0.64) GABRA1GABRB2AKR1B1POLBMAPK1
Formaldehyde SCHEMBL14742618 0.88 GABRA1 (0.57) GABRA1GABRB2AKR1B1POLBMAPK1
SCHEMBL27513033 0.88 GABRA1 (0.61) GABRA1GABRB2AKR1B1POLBMAPK1
Methoxymethane SCHEMBL29084367 0.84 GABRA1 (0.57) GABRA1GABRB2AKR1B1POLBMAPK1
Bicarbonate SCHEMBL27740095 0.84 HSPA5 (0.55) GABRA1GABRB2AKR1B1POLBMAPK1
Bicarbonate SCHEMBL27568192 0.81 GABRA1 (0.58) GABRA1GABRB2AKR1B1RAB9ATSHR
SCHEMBL15942178 0.81 AKR1B1 (0.48) GABRA1GABRB2AKR1B1POLBMAPK1
SCHEMBL5311363 0.81 POLB (0.57) AKR1B1POLBMAPK1HSPA5ELANE
Acetic Acid SCHEMBL27895243 0.79 AKR1B1 (0.61) GABRA1GABRB2AKR1B1HSPA5CYP2D6
SCHEMBL10457141 0.79 AKR1B1 (0.52) AKR1B1POLBMAPK1HSPA5MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4299705-B1 A PROCESS FOR MAKING A COMPOSITION COMPRISING ALKYL POLYGLYCOSIDE AND PERFUME PROCTER & GAMBLE (US) 2025-12-17 EP disclosed
EP-4299705-A1 A PROCESS FOR MAKING A COMPOSITION COMPRISING ALKYL POLYGLYCOSIDE AND PERFUME The Procter & Gamble Company (US) 2024-01-03 EP disclosed
US-20230414474-A1 PROCESS FOR MAKING A COMPOSITION COMPRISING ALKYL POLYGLYCOSIDE AND PERFUME THE PROCTER & GAMBLE COMPANY 2023-12-28 US disclosed
EP-0075976-B1 ALKALINE AQUEOUS LIQUID DETERGENT COMPOSITIONS CONTAINING NORMALLY UNSTABLE ESTER PERFUMES THE PROCTER & GAMBLE COMPANY (US) 1985-06-19 EP disclosed
US-4440663-A Alkaline aqueous liquid detergent compositions containing normally unstable ester perfumes THE PROCTER & GAMBLE COMPANY (US) 1984-04-03 US disclosed
EP-0075976-A1 Alkaline aqueous liquid detergent compositions containing normally unstable ester perfumes THE PROCTER & GAMBLE COMPANY (US) 1983-04-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230414474-A1 PROCESS FOR MAKING A COMPOSITION COMPRISING ALKYL POLYGLYCOSIDE AND PERFUME FUT8, PLG, PIGS GABRA1 2480/4885GABRB2 2246/4885AKR1B1 610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.