SCHEMBL1102556

SCHEMBL1102556

C1=Cc2ccc(-c3c4ccccc4c(-c4ccc5c(c4)N(c4ccccc4)c4ccccc4C=C5)c4cnccc34)cc2N(c2ccccc2)c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 2/20 0.33
P2RX4 Q99571 1/20 0.32
GSK3B P49841 1/20 0.31
KCNH2 Q12809 1/20 0.31
MDM2 Q00987 1/20 0.31
CDK4 P11802 1/20 0.30
CCND1 P24385 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1102691 0.86 DYRK1A (0.36) DYRK1AGSK3BKCNH2MDM2CDK4
SCHEMBL12886826 0.84 KDM4C (0.31)
SCHEMBL12886774 0.84 GRIN2D (0.31)
SCHEMBL12887088 0.84 DYRK1A (0.30) DYRK1A
SCHEMBL12887169 0.83 MAPK9 (0.31)
SCHEMBL1102886 0.83 HTT (0.32)
SCHEMBL1102778 0.82 P2RX4 (0.35) P2RX4
SCHEMBL1102768 0.81 ACHE (0.37) DYRK1AGSK3BKCNH2CDK4CCND1
SCHEMBL1102524 0.80 CDK8 (0.34) DYRK1AGSK3BKCNH2CDK4CCND1
SCHEMBL1102692 0.80 ADRA2A (0.37) DYRK1AGSK3BKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153279-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2012-04-10 US disclosed
US-8153279-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2012-04-10 US disclosed
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed
EP-2147962-A1 Azaanthracene-derivatives and organic electroluminescent device using the same Gracel Display Inc. (KR) 2010-01-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same ORMDL3, OCIAD2, OCIAD1 DYRK1A 4241/4885P2RX4 1489/4885GSK3B 3423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.