Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of 2-Ethoxyethanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.93 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Ethoxyethanol SCHEMBL1123166 | 1.00 | — | — | |
| 2-Ethoxyethanol SCHEMBL10343650 | 0.97 | ALDH1A1 (0.88) | ALDH1A1TSHRMAPK1KMT2AMEN1 | |
| 2-Ethoxyethanol SCHEMBL9547497 | 0.97 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPK1KMT2AMEN1 | |
| 2-Ethoxyethanol SCHEMBL4686 | 0.97 | — | — | |
| 2-Ethoxyethanol SCHEMBL9432157 | 0.97 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPK1KMT2AMEN1 | |
| 2-Ethoxyethanol SCHEMBL11024472 | 0.97 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPK1KMT2AMEN1 | |
| Diethylene Glycol Monoethyl Ether SCHEMBL1123497 | 0.94 | ALDH1A1 (0.82) | ALDH1A1TSHRMAPK1KMT2AMEN1 | |
| Diethylene Glycol Monoethyl Ether SCHEMBL8014385 | 0.94 | ALDH1A1 (0.82) | ALDH1A1TSHRMAPK1KMT2AMEN1 | |
| Di(Hydroxyethyl)Ether SCHEMBL6550626 | 0.93 | ALDH1A1 (0.93) | ALDH1A1TSHRMAPK1KMT2AMEN1 | |
| 2-Ethoxyethanol SCHEMBL337831 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4503907-A | Heat exchanger coated with aqueous coating composition | HITACHI, LTD. (JP) | 1985-03-12 | — | — | US | disclosed |