Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 1/20 | 0.31 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.31 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28354684 | 0.58 | APEX1 (0.34) | — | |
| SCHEMBL11026230 | 0.58 | KDM4E (0.34) | DAOKDM4ENPSR1 | |
| SCHEMBL925336 | 0.56 | HTT (0.45) | KDM4ETSHR | |
| SCHEMBL5647 | 0.53 | ADORA2A (0.43) | KDM4ENPSR1TSHR | |
| SCHEMBL8937183 | 0.53 | KDM4E (0.43) | KDM4ENPSR1TSHR | |
| SCHEMBL4621732 | 0.52 | ADORA2A (0.43) | DAOKDM4ETSHR | |
| SCHEMBL10730940 | 0.51 | KDM4E (0.51) | DAOKDM4ETSHR | |
| SCHEMBL1945331 | 0.51 | KDM4E (0.64) | KDM4E | |
| SCHEMBL15564466 | 0.50 | DAO (0.51) | DAOTSHR | |
| SCHEMBL15564414 | 0.50 | GRIA1 (0.50) | DAOTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103497-B1 | XANTHINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR (FR) | 1986-01-29 | — | — | EP | disclosed |
| EP-0103497-A1 | Xanthine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1984-03-21 | — | — | EP | disclosed |