Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2462138 | 0.76 | KDM4E (0.40) | KDM4EALDH1A1MEN1LMNAGAA | |
| SCHEMBL3604453 | 0.60 | MAPT (0.30) | MAPT | |
| SCHEMBL11293666 | 0.59 | KDM4E (0.36) | KDM4EALDH1A1MEN1LMNAGAA | |
| SCHEMBL19987789 | 0.58 | EPHX2 (0.30) | — | |
| SCHEMBL28354684 | 0.58 | APEX1 (0.34) | MAPT | |
| SCHEMBL11026229 | 0.58 | CXCL8 (0.31) | KDM4EDAONPSR1 | |
| SCHEMBL1945331 | 0.57 | KDM4E (0.64) | KDM4EALDH1A1MEN1LMNAGAA | |
| SCHEMBL20865055 | 0.57 | ALDH1A1 (0.46) | KDM4EALDH1A1MEN1LMNAGAA | |
| SCHEMBL11477500 | 0.56 | HPRT1 (0.31) | — | |
| SCHEMBL11295506 | 0.56 | MEN1 (0.51) | KDM4EALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103497-B1 | XANTHINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR (FR) | 1986-01-29 | — | — | EP | disclosed |
| EP-0103497-A1 | Xanthine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1984-03-21 | — | — | EP | disclosed |