Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PDE1A | P54750 | 3/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.42 |
| ▸ | PDE2A | O00408 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7624092 | 0.84 | KDM4E (0.42) | KDM4ENPSR1PDE1APDE1BPDE1C | |
| SCHEMBL4623478 | 0.83 | KDM4E (0.38) | KDM4ENPSR1PDE1APDE1BPDE1C | |
| SCHEMBL1804901 | 0.82 | KDM4E (0.41) | KDM4ENPSR1PDE1APDE1BPDE1C | |
| SCHEMBL2476718 | 0.81 | MEN1 (0.45) | KDM4ENPSR1PDE1APDE1BPDE1C | |
| SCHEMBL8642882 | 0.74 | ALDH1A1 (0.43) | KDM4ENPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL5647 | 0.73 | ADORA2A (0.43) | KDM4ENPSR1PDE1APDE1BPDE1C | |
| SCHEMBL9765951 | 0.72 | ADORA2A (0.49) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL4796600 | 0.70 | PDE4A (0.47) | KDM4EPDE1APDE1BPDE1CPDE2A | |
| SCHEMBL23797830 | 0.70 | HTT (0.42) | KDM4EPDE1APDE1BPDE1CPDE2A | |
| SCHEMBL4623658 | 0.69 | PDE4A (0.39) | KDM4ENPSR1PDE1APDE1BPDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525329-A | INCREASED SENSITIVITY TO ODORS | THE JOHNS HOPKINS UNIVERSITY (US) | 1996-06-11 | — | — | US | claimed |