SCHEMBL11026294

SCHEMBL11026294

CCCCCCCCC(CCCCCCCC)O[Si](CCCCCCCC)(OC)OC

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
ZDHHC7 Q9NXF8 1/20 0.34
DNM1 Q05193 2/20 0.32
SMPD1 P17405 3/20 0.32
OPRM1 P35372 1/20 0.31
TSHR P16473 1/20 0.31
THRB P10828 1/20 0.31
FDPS P14324 3/20 0.31
GPR84 Q9NQS5 2/20 0.31
SPHK1 Q9NYA1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14656890 1.00 LMNA (0.46) LMNAZDHHC7DNM1SMPD1OPRM1
SCHEMBL28492495 1.00 LMNA (0.46) LMNAZDHHC7DNM1SMPD1OPRM1
SCHEMBL28496866 1.00 LMNA (0.46) LMNAZDHHC7DNM1SMPD1OPRM1
SCHEMBL2761426 0.90 LMNA (0.41) LMNADNM1TSHRSPHK1
SCHEMBL7757142 0.88 LMNA (0.40) LMNADNM1
SCHEMBL28550781 0.88 LMNA (0.40) LMNADNM1TSHRSPHK1
SCHEMBL29210230 0.86 LMNA (0.39) LMNAZDHHC7DNM1SMPD1OPRM1
SCHEMBL28124336 0.85 LMNA (0.40) LMNAZDHHC7DNM1SMPD1
SCHEMBL27845806 0.84 LMNA (0.37) LMNAZDHHC7
SCHEMBL1055825 0.84 LMNA (0.37) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111372992-A Method for improving visibility of contents, vinyl chloride resin composition, molded article, stabilizer, medical material, and method for sterilization treatment 新日本理化株式会社 2020-07-03 CN disclosed
EP-2483354-B1 METHOD FOR SEPARATING SUBSTANCE MIXTURES BY MEANS OF MULTIPHASE POLYMER FILMS BASF SE (DE) 2013-08-28 EP disclosed
US-20120187045-A1 METHOD FOR SEPARATING SUBSTANCE MIXTURES BY MEANS OF MULTIPHASE POLYMER FILMS BASF SE (DE) 2012-07-26 US disclosed