Phosphonic Acid

Phosphonic Acid

SCHEMBL11026461

CNC(=O)C(N)=O.O=[PH](O)O

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.30
LMNA P02545 1/20 0.30
ALOX15 P16050 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL210049 0.88
Hydrochloric Acid SCHEMBL27575069 0.85
Phosphonic Acid SCHEMBL3430058 0.79
Formic Acid SCHEMBL9358830 0.78 KDM4E (0.33) TDP1LMNAALOX15BLMPMP22
Alcohol SCHEMBL11338702 0.78 TGFBR1 (0.38) TDP1LMNAALOX15BLMPMP22
Phosphonic Acid SCHEMBL11026022 0.74 KDM5B (0.40)
SCHEMBL11881495 0.71
SCHEMBL4688014 0.70 ALDH1A1 (0.46) TDP1
Phosphonic Acid SCHEMBL11023728 0.70 TET2 (0.39)
Phosphonic Acid SCHEMBL375803 0.70 ALDH1A1 (0.36) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0063411-B1 SUBSTITUTED METHANEPHOSHONIC ACID DERIVATIVES, THEIR USE AS HERBICIDES, HERBICIDAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR PREPARING THEM IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-06-05 EP disclosed
US-4454073-A HERBICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-06-12 US disclosed
EP-0063411-A1 Substituted methanephoshonic acid derivatives, their use as herbicides, herbicidal compositions containing them, and processes for preparing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-10-27 EP disclosed