Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KHK | P50053 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10572188 | 0.86 | KDM4E (0.47) | KDM4EGAAKHK | |
| SCHEMBL10574630 | 0.84 | KDM4E (0.48) | KDM4EGAAKHK | |
| SCHEMBL9787094 | 0.82 | KDM4E (0.38) | KDM4EGAA | |
| SCHEMBL6443989 | 0.78 | KDM4E (0.57) | KDM4EGAA | |
| SCHEMBL29705235 | 0.78 | KDM4E (0.57) | KDM4EGAA | |
| SCHEMBL28808893 | 0.78 | KDM4E (0.57) | KDM4EGAA | |
| SCHEMBL9787165 | 0.77 | KDM4E (0.42) | KDM4EGAAKHK | |
| SCHEMBL11026950 | 0.77 | KDM4E (0.38) | KDM4EGAA | |
| SCHEMBL11026618 | 0.77 | KDM4E (0.47) | KDM4EGAAKHK | |
| SCHEMBL8642384 | 0.74 | KDM4E (0.53) | KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104788368-B | The preparation method of the formic acid esters of 4 amino, 3 chlorine 5 fluorine 6 (substituted) pyridine 2 | 陶氏益农公司 | 2017-09-26 | — | — | CN | disclosed |
| EP-2668163-B1 | PROCESS FOR THE PREPARATION OF 6-SUBSTITUTED 4-AMINO-3-CHLORO-5-FLUORO-PICOLINATES | DOW AGROSCIENCES LLC (US) | 2017-05-10 | — | — | EP | disclosed |
| EP-2668163-B1 | PROCESS FOR THE PREPARATION OF 6-SUBSTITUTED 4-AMINO-3-CHLORO-5-FLUORO-PICOLINATES | DOW AGROSCIENCES LLC (US) | 2017-05-10 | — | — | EP | disclosed |
| US-9598368-B2 | Process for the preparation of 4-amino-3-chloro-5-fluoro-6-(substituted)picolinates | DOW AGROSCIENCES LLC (US) | 2017-03-21 | — | — | US | disclosed |
| US-9598368-B2 | Process for the preparation of 4-amino-3-chloro-5-fluoro-6-(substituted)picolinates | DOW AGROSCIENCES LLC (US) | 2017-03-21 | — | — | US | disclosed |
| US-9598368-B2 | Process for the preparation of 4-amino-3-chloro-5-fluoro-6-(substituted)picolinates | DOW AGROSCIENCES LLC (US) | 2017-03-21 | — | — | US | disclosed |
| EP-2901857-B1 | Process for the preparation of 3-chloro-4,5,6-trifluoro-picolinonitrile | DOW AGROSCIENCES LLC (US) | 2017-03-01 | — | — | EP | disclosed |
| EP-2901857-B1 | Process for the preparation of 3-chloro-4,5,6-trifluoro-picolinonitrile | DOW AGROSCIENCES LLC (US) | 2017-03-01 | — | — | EP | disclosed |
| US-9452984-B2 | Process for the preparation of 4-amino-3-chloro-5-fluoro-6-(substituted) picolinates | DOW AGROSCIENCES LLC (US) | 2016-09-27 | — | — | US | disclosed |
| US-9452984-B2 | Process for the preparation of 4-amino-3-chloro-5-fluoro-6-(substituted) picolinates | DOW AGROSCIENCES LLC (US) | 2016-09-27 | — | — | US | disclosed |
| EP-2667713-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-3-CHLORO-5-FLUORO-6-(SUBSTITUTED)PICOLINATES | Dow AgroSciences LLC (US) | 2013-12-04 | — | — | EP | disclosed |
| EP-2668163-A2 | PROCESS FOR THE PREPARATION OF 4-AMINO-3-CHLORO-5-FLUORO-6-(SUBSTITUTED) PICOLINATES | Dow AgroSciences LLC (US) | 2013-12-04 | — | — | EP | disclosed |
| CN-103429082-A | Process for the preparation of 4-amino-3-chloro-5-fluoro-6-(substituted)picolinates | DOW AGROSCIENCES LLC | 2013-12-04 | — | — | CN | disclosed |
| WO-2012103041-A2 | PROCESS FOR THE PREPARATION OF 4-AMINO-3-CHLORO-5-FLUORO-6-(SUBSTITUTED) PICOLINATES | DOW AGROSCIENCES LLC (US) | 2012-08-02 | — | — | WO | disclosed |
| WO-2012103044-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-3-CHLORO-5-FLUORO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2012-08-02 | — | — | WO | disclosed |
| US-20120190858-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-3-CHLORO-5-FLUORO-6-(SUBSTITUTED) PICOLINATES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190858-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-3-CHLORO-5-FLUORO-6-(SUBSTITUTED) PICOLINATES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190858-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-3-CHLORO-5-FLUORO-6-(SUBSTITUTED) PICOLINATES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190857-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-3-CHLORO-5-FLUORO-6-(SUBSTITUTED) PICOLINATES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190857-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-3-CHLORO-5-FLUORO-6-(SUBSTITUTED) PICOLINATES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190858-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-3-CHLORO-5-FLUORO-6-(SUBSTITUTED) PICOLINATES | CYP4F3, CYP4F12, CYP4F8 | KDM4E 684/4885GAA 2011/4885KHK 396/4885 |
| US-20120190857-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-3-CHLORO-5-FLUORO-6-(SUBSTITUTED) PICOLINATES | CYP4F3, AFF4, CYP4F12 | KDM4E 732/4885GAA 1937/4885KHK 571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.