SCHEMBL29705235

SCHEMBL29705235

N#Cc1nc(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.57
GAA P10253 2/20 0.57
ALDH1A1 P00352 3/20 0.38
CYP3A4 P08684 2/20 0.38
HPGD P15428 2/20 0.38
MEN1 O00255 1/20 0.38
TP53 P04637 1/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ALOX15 P16050 2/20 0.30
NPC1 O15118 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
ALOX12 P18054 1/20 0.30
CYP2C19 P33261 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28808893 1.00 KDM4E (0.57) KDM4EGAAALDH1A1CYP3A4HPGD
SCHEMBL6443989 1.00 KDM4E (0.57) KDM4EGAAALDH1A1CYP3A4HPGD
SCHEMBL70226 0.86 KDM4E (0.46) KDM4EGAAALDH1A1CYP3A4HPGD
SCHEMBL2051824 0.80 KDM4E (0.48) KDM4EGAAALDH1A1CYP3A4HPGD
SCHEMBL10574630 0.80 KDM4E (0.48) KDM4EGAA
SCHEMBL8642384 0.80 KDM4E (0.53) KDM4EGAAALDH1A1CYP3A4HPGD
SCHEMBL19283130 0.78 KDM4E (0.47) KDM4EGAAALDH1A1HPGDMEN1
SCHEMBL18836991 0.78 KDM4E (0.52) KDM4EGAAALDH1A1CYP3A4HPGD
SCHEMBL11026802 0.78 KDM4E (0.52) KDM4EGAA
SCHEMBL21860793 0.78 KDM4E (0.57) KDM4EGAAALDH1A1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118217896-A Continuous reaction device and method for continuously preparing 4-amino-3, 5, 6-trichloropyridine nitrile 北京颖泰嘉和生物科技股份有限公司 2024-06-21 CN claimed
CN-114702440-B Preparation method of picloram and picloram prepared by same 永农生物科学有限公司 2024-06-18 CN disclosed
CN-115677011-B Process for treating chloropyridine pesticide wastewater 浙江卓锦环保科技股份有限公司 2024-06-11 CN disclosed
CN-113912533-B Method for preparing 3, 6-dichloropicolinic acid 西安凯立新材料股份有限公司 2023-06-20 CN disclosed
CN-114702440-A Preparation method of picloram and picloram prepared by same 永农生物科学有限公司 2022-07-05 CN disclosed