Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29705235 | 1.00 | KDM4E (0.57) | KDM4EGAAALDH1A1CYP3A4HPGD | |
| SCHEMBL28808893 | 1.00 | KDM4E (0.57) | KDM4EGAAALDH1A1CYP3A4HPGD | |
| SCHEMBL70226 | 0.86 | KDM4E (0.46) | KDM4EGAAALDH1A1CYP3A4HPGD | |
| SCHEMBL2051824 | 0.80 | KDM4E (0.48) | KDM4EGAAALDH1A1CYP3A4HPGD | |
| SCHEMBL10574630 | 0.80 | KDM4E (0.48) | KDM4EGAA | |
| SCHEMBL8642384 | 0.80 | KDM4E (0.53) | KDM4EGAAALDH1A1CYP3A4HPGD | |
| SCHEMBL19283130 | 0.78 | KDM4E (0.47) | KDM4EGAAALDH1A1HPGDMEN1 | |
| SCHEMBL18836991 | 0.78 | KDM4E (0.52) | KDM4EGAAALDH1A1CYP3A4HPGD | |
| SCHEMBL11026802 | 0.78 | KDM4E (0.52) | KDM4EGAA | |
| SCHEMBL21860793 | 0.78 | KDM4E (0.57) | KDM4EGAAALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119798152-A | Preparation method of tetrachloropicolinic acid | 江阴苏利化学股份有限公司 | 2025-04-11 | — | — | CN | claimed |
| CN-119776329-A | Nitrilase mutant and application thereof in hydrolysis of pyridine nitrile derivatives | 浙江工业大学 | 2025-04-08 | — | — | CN | claimed |
| CN-119410626-A | Magnetic nitrilase catalyst for green cyclic synthesis of organic acid, preparation method and application thereof | 浙江工业大学 | 2025-02-11 | — | — | CN | claimed |
| CN-117965504-A | Nitrilase mutant and application thereof in preparation of chloropyridine carboxylic acid | 浙江工业大学 | 2024-05-03 | — | — | CN | claimed |
| CN-117683754-A | Nitrilase mutant and application thereof in pesticide synthesis | 浙江工业大学 | 2024-03-12 | — | — | CN | claimed |
| CN-109092091-B | Mixer for producing 3,4,5, 6-tetrachloro-2-cyanopyridine | 湖南比德生化科技股份有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-107325046-B | Liquid phase chlorination production process and device for tetrachloro-2-cyanopyridine | 南京大学 | 2023-04-07 | — | — | CN | claimed |
| EP-2668163-B1 | PROCESS FOR THE PREPARATION OF 6-SUBSTITUTED 4-AMINO-3-CHLORO-5-FLUORO-PICOLINATES | DOW AGROSCIENCES LLC (US) | 2017-05-10 | — | — | EP | claimed |
| US-9598368-B2 | Process for the preparation of 4-amino-3-chloro-5-fluoro-6-(substituted)picolinates | DOW AGROSCIENCES LLC (US) | 2017-03-21 | — | — | US | claimed |
| EP-2901857-B1 | Process for the preparation of 3-chloro-4,5,6-trifluoro-picolinonitrile | DOW AGROSCIENCES LLC (US) | 2017-03-01 | — | — | EP | claimed |
| CN-102070519-B | Method for purifying 3,4,5,6-tetrachloro-2-cyanopyridine by sublimation and catching, and catcher and system thereof | HENGDIAN GROUP DONGYANG INNUOVO GREEN ELECTRICITY CHEMICAL CO LTD | 2012-10-10 | — | — | CN | claimed |
| WO-2012103041-A2 | PROCESS FOR THE PREPARATION OF 4-AMINO-3-CHLORO-5-FLUORO-6-(SUBSTITUTED) PICOLINATES | DOW AGROSCIENCES LLC (US) | 2012-08-02 | — | — | WO | claimed |
| WO-2012103044-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-3-CHLORO-5-FLUORO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2012-08-02 | — | — | WO | claimed |
| US-20120190858-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-3-CHLORO-5-FLUORO-6-(SUBSTITUTED) PICOLINATES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | claimed |
| US-20120190857-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-3-CHLORO-5-FLUORO-6-(SUBSTITUTED) PICOLINATES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | claimed |
| CN-102070519-A | Method for purifying 3,4,5,6-tetrachloro-2-cyanopyridine by sublimation and catching, and catcher and system thereof | HENGDIAN GROUP DONGYANG INNUOVO GREEN ELECTRICITY CHEMICAL CO LTD | 2011-05-25 | — | — | CN | claimed |
| US-4766219-A | Preparation of 2-cyano-6-chloropyridine compounds | THE DOW CHEMICAL COMPANY (US) | 1988-08-23 | — | — | US | claimed |
| EP-0063780-A1 | Preparation of 4-amino-3,5,6-trichloropicolinic acid | THE DOW CHEMICAL COMPANY (US) | 1982-11-03 | — | — | EP | claimed |
| US-4336384-A | Preparation of 4-amino-3,5,6-trichloropicolinic acid | THE DOW CHEMICAL COMPANY (US) | 1982-06-22 | — | — | US | claimed |
| US-4087431-A | Preparation of 3,6-dichloropicolinic acid | THE DOW CHEMICAL COMPANY (US) | 1978-05-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190858-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-3-CHLORO-5-FLUORO-6-(SUBSTITUTED) PICOLINATES | CYP4F3, CYP4F12, CYP4F8 | KDM4E 684/4885GAA 2011/4885ALDH1A1 1387/4885 |
| US-20120190857-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-3-CHLORO-5-FLUORO-6-(SUBSTITUTED) PICOLINATES | CYP4F3, AFF4, CYP4F12 | KDM4E 732/4885GAA 1937/4885ALDH1A1 2604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.