Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | DRD3 | P35462 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | BRD4 | O60885 | 1/20 | 0.61 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.57 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.57 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11391733 | 0.91 | ALDH1A1 (0.86) | ALDH1A1DRD3KDM4EHSD17B10MEN1 | |
| 4-N-Acetyl-1-Piperazinyl-Norfloxacin SCHEMBL11027379 | 0.90 | HSD17B10 (0.83) | ALDH1A1DRD3KDM4EHSD17B10MEN1 | |
| 4-N-Acetyl-1-Piperazinyl-Norfloxacin SCHEMBL30570718 | 0.90 | HSD17B10 (0.83) | ALDH1A1DRD3KDM4EHSD17B10MEN1 | |
| SCHEMBL11026160 | 0.88 | ALDH1A1 (0.65) | ALDH1A1DRD3KDM4EHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL11026207 | 0.84 | ALDH1A1 (0.77) | ALDH1A1DRD3KDM4EHSD17B10MEN1 | |
| SCHEMBL7809357 | 0.83 | ALDH1A1 (1.00) | ALDH1A1DRD3KDM4EHSD17B10MEN1 | |
| SCHEMBL29388444 | 0.83 | ALDH1A1 (1.00) | ALDH1A1DRD3KDM4EHSD17B10MEN1 | |
| SCHEMBL15282135 | 0.82 | ALDH1A1 (0.86) | ALDH1A1DRD3KDM4EHSD17B10MEN1 | |
| SCHEMBL22698592 | 0.82 | HSD17B10 (0.84) | ALDH1A1DRD3KDM4EHSD17B10MEN1 | |
| SCHEMBL9636841 | 0.82 | KDM4E (0.71) | ALDH1A1DRD3KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448962-A | BACTERICIDES | KYORIN SEIYAKU KABUSHIKI KAISHA | 1984-05-15 | — | — | US | disclosed |