Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.54 |
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9635302 | 0.91 | KDM4E (0.70) | KDM4EALDH1A1HSD17B10HPGDPMP22 | |
| SCHEMBL312186 | 0.91 | KDM4E (0.86) | KDM4EALDH1A1HSD17B10HPGDPMP22 | |
| SCHEMBL11187032 | 0.88 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10HPGDPMP22 | |
| Hydrochloric Acid SCHEMBL11187784 | 0.86 | KDM4E (0.68) | KDM4EALDH1A1HSD17B10HPGDPMP22 | |
| SCHEMBL11182346 | 0.84 | KDM4E (0.68) | KDM4EALDH1A1HSD17B10HPGDPMP22 | |
| Fleroxacin SCHEMBL29377022 | 0.83 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10HPGDPMP22 | |
| Fleroxacin SCHEMBL48145 | 0.83 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10HPGDPMP22 | |
| Fleroxacin SCHEMBL9745354 | 0.82 | KDM4E (0.98) | KDM4EALDH1A1HSD17B10HPGDPMP22 | |
| SCHEMBL21783262 | 0.82 | KDM4E (0.86) | KDM4EALDH1A1HSD17B10HPGDPMP22 | |
| Fleroxacin SCHEMBL11193870 | 0.82 | KDM4E (0.98) | KDM4EALDH1A1HSD17B10HPGDPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195135-B1 | A PROCESS FOR THE PREPARATION OF QUINOLINE CARBOXYLIC ACID DERIVATIVES | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1992-06-17 | — | — | EP | disclosed |