SCHEMBL11027461

SCHEMBL11027461

CC(C(c1ccccc1)c1ccccc1)C(c1ccc(OCCO)cc1)c1ccc(OCCO)cc1

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.58
RECQL P46063 1/20 0.58
GAA P10253 2/20 0.50
GPR88 Q9GZN0 6/20 0.45
NR1I2 O75469 1/20 0.45
CYP19A1 P11511 1/20 0.43
LTA4H P09960 1/20 0.42
HPGD P15428 1/20 0.42
ADRB2 P07550 1/20 0.41
ADRB1 P08588 1/20 0.41
ADRB3 P13945 1/20 0.41
CYP3A4 P08684 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
FFAR1 O14842 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8408712 0.86 ALDH1A1 (0.62) ALDH1A1RECQLGAAGPR88NR1I2
SCHEMBL21903452 0.82 ALDH1A1 (0.67) ALDH1A1RECQLGAAGPR88NR1I2
SCHEMBL5390591 0.81 ALDH1A1 (0.60) ALDH1A1RECQLGAAGPR88NR1I2
SCHEMBL6901305 0.81 ALDH1A1 (0.64) ALDH1A1RECQLGAAGPR88NR1I2
SCHEMBL5551011 0.78 RAB9A (0.54) ALDH1A1RECQLGAANR1I2ADRB2
SCHEMBL347372 0.78 ALDH1A1 (0.54) ALDH1A1RECQLGAANR1I2ADRB2
SCHEMBL8415622 0.78 GAA (0.55) ALDH1A1RECQLGAAGPR88
SCHEMBL28815995 0.78 ALDH1A1 (0.50) ALDH1A1RECQLGAAGPR88CYP3A4
SCHEMBL17915614 0.77 ALDH1A1 (0.50) ALDH1A1RECQLGAAGPR88NR1I2
Phenoxyethanol SCHEMBL7078024 0.76 ALDH1A1 (0.91) ALDH1A1RECQLGAANR1I2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4455426-A CATALYST FOR HARDENING EPOXY RESINS BAYER AKTIENGESELLSCHAFT (DE) 1984-06-19 US disclosed
US-4455425-A EPOXY RESINS, CURING AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1984-06-19 US disclosed
US-4424353-A INTERMEDIATES FOR ISOCYANATE ADDUCTS, EPOXY RESIN CURING AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1984-01-03 US disclosed