Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8596072 | 0.93 | CA2 (0.51) | CA2RAB9ALMNAGAAALDH1A1 | |
| SCHEMBL8282396 | 0.85 | CA2 (0.59) | CA2FFAR1RAB9ALMNAGAA | |
| SCHEMBL6984001 | 0.83 | CA2 (0.58) | CA2FFAR1RAB9ALMNAGAA | |
| SCHEMBL15870243 | 0.83 | CA2 (0.58) | CA2FFAR1RAB9ALMNAGAA | |
| SCHEMBL29481813 | 0.83 | CA2 (0.58) | CA2FFAR1RAB9ALMNAGAA | |
| SCHEMBL17272701 | 0.83 | CA2 (0.58) | CA2FFAR1RAB9ALMNAGAA | |
| SCHEMBL29444746 | 0.83 | CA2 (0.58) | CA2FFAR1RAB9ALMNAGAA | |
| SCHEMBL6984007 | 0.83 | CA2 (0.58) | CA2FFAR1RAB9ALMNAGAA | |
| SCHEMBL11025999 | 0.81 | CA2 (0.59) | CA2FFAR1RAB9A | |
| SCHEMBL8259889 | 0.81 | CA2 (0.56) | CA2FFAR1RAB9ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068261-B1 | N-OXACYCLYL-ALKYLPIPERIDINE DERIVATIVES, THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-04-03 | — | — | EP | disclosed |
| US-4470989-A | Neuroleptic n-oxacyclyl-alkylpiperidine derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-11 | — | — | US | disclosed |
| EP-0068261-A1 | N-oxacyclyl-alkylpiperidine derivatives, their preparation, pharmaceutical preparations containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-01-05 | — | — | EP | disclosed |