Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11027482 | 0.93 | CA2 (0.58) | CA2RAB9ALMNAGAAALDH1A1 | |
| SCHEMBL1107087 | 0.83 | CA2 (0.51) | CA2RAB9ALMNAGAA | |
| SCHEMBL1107090 | 0.83 | CA2 (0.51) | CA2RAB9ALMNAGAA | |
| SCHEMBL8288367 | 0.83 | CA2 (0.51) | CA2RAB9ALMNAGAA | |
| SCHEMBL9116625 | 0.83 | CA2 (0.55) | CA2CA1RAB9ALMNAGAA | |
| SCHEMBL9117176 | 0.81 | CA2 (0.59) | CA2CA1RAB9A | |
| SCHEMBL11222928 | 0.81 | CA2 (0.49) | CA2RAB9ALMNAGAAHTT | |
| SCHEMBL12863053 | 0.78 | LMNA (0.49) | CA2RAB9ALMNAGAA | |
| SCHEMBL8282396 | 0.78 | CA2 (0.59) | CA2RAB9ALMNAGAAALDH1A1 | |
| SCHEMBL17815971 | 0.77 | CA2 (0.46) | CA2RAB9ALMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565732-B1 | BENZODIOXANE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1998-01-14 | — | — | EP | disclosed |
| US-5480905-A | ANTIDEPRESSANTS, ANXIOLYTIC AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0565732-A1 | BENZODIOXANE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 1993-10-20 | — | — | EP | disclosed |
| EP-0068261-B1 | N-OXACYCLYL-ALKYLPIPERIDINE DERIVATIVES, THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-04-03 | — | — | EP | disclosed |
| US-4470989-A | Neuroleptic n-oxacyclyl-alkylpiperidine derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-11 | — | — | US | disclosed |
| EP-0068261-A1 | N-oxacyclyl-alkylpiperidine derivatives, their preparation, pharmaceutical preparations containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-01-05 | — | — | EP | disclosed |