SCHEMBL11027696

SCHEMBL11027696

CCOP(=S)(OCC)N(C)S(C)(=O)=O

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.36
TSHR P16473 3/20 0.36
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
TP53 P04637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11511618 0.83 TSHR (0.33) ACHETSHRMEN1KMT2ATP53
SCHEMBL11512443 0.78 TP53 (0.32) TSHRTP53TDP1
SCHEMBL11593527 0.78 TSHR (0.30) TSHR
Potassium Ion SCHEMBL11221285 0.78 ACHE (0.33) ACHETSHR
SCHEMBL11511964 0.77 TSHR (0.32) ACHETSHRTP53TDP1
SCHEMBL11025941 0.75 TSHR (0.31) ACHETSHR
SCHEMBL11514793 0.75 NPC1 (0.31) TP53POLB
SCHEMBL11515124 0.75 LMNA (0.32) TSHR
SCHEMBL11514059 0.72 MEN1 (0.33) ACHEMEN1KMT2A
SCHEMBL11513509 0.71 TDP1 (0.42) TSHRMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0061679-B1 N-SULFONYLATED THIOL PHOSPHORIC ACID AMIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES BASF Aktiengesellschaft (DE) 1985-08-28 EP disclosed
US-4161524-A INSECTICIDES, MITICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-07-17 US disclosed
US-4150155-A INSECTICIDES, NEMATOCIDES, MITICIDES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1979-04-17 US disclosed
US-4134979-A INSECTICIDES, MITICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-01-16 US disclosed