Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.38 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 8/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28725545 | 0.86 | TSHR (0.35) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL695768 | 0.86 | TSHR (0.42) | TSHRGGPS1FDPSCES2 | |
| SCHEMBL8764175 | 0.82 | TSHR (0.38) | TSHRGGPS1FDPSCES2 | |
| SCHEMBL12808397 | 0.80 | TSHR (0.36) | TSHRGGPS1FDPSCES2 | |
| SCHEMBL13696917 | 0.78 | TSHR (0.35) | TSHRGGPS1FDPSCES2 | |
| SCHEMBL25729202 | 0.77 | TSHR (0.46) | MEN1KMT2ATSHRGGPS1FDPS | |
| SCHEMBL7616020 | 0.76 | TSHR (0.41) | LMNAALDH1A1TSHRFDPS | |
| SCHEMBL7877972 | 0.74 | SMN1; SMN2 (0.35) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL28081146 | 0.74 | TSHR (0.39) | LMNATSHRFDPS | |
| SCHEMBL11282752 | 0.74 | LMNA (0.34) | LMNAALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356128-A | WETTING AGENT FOR PIGMENTS IN POLYURETHANE COATING COMPOSITIONS | HENKEL CORPORATION (US) | 1982-10-26 | — | — | US | claimed |
| EP-0063944-B1 | POLYHYDRIC ALCOHOLS | HENKEL CORPORATION (a Delaware corp.) (US) | 1985-07-10 | — | — | EP | disclosed |
| EP-0063944-A1 | Polyhydric alcohols | HENKEL CORPORATION (a Delaware corp.) (US) | 1982-11-03 | — | — | EP | disclosed |
| US-4356128-A | WETTING AGENT FOR PIGMENTS IN POLYURETHANE COATING COMPOSITIONS | HENKEL CORPORATION (US) | 1982-10-26 | — | — | US | disclosed |