Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.51 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | F7 | P08709 | 3/20 | 0.41 |
| ▸ | F3 | P13726 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11028146 | 1.00 | RARB (0.51) | RARBTNNC1PPARATRPM2PDE5A | |
| SCHEMBL10635749 | 0.94 | RARB (0.47) | RARBTNNC1PPARATRPM2PDE5A | |
| SCHEMBL20556305 | 0.88 | RARB (0.43) | RARBTRPM2ALDH1A1KDM4ETDP1 | |
| SCHEMBL20556511 | 0.88 | RARB (0.43) | RARBTRPM2ALDH1A1KDM4ETDP1 | |
| SCHEMBL20556303 | 0.88 | RARB (0.43) | RARBTRPM2ALDH1A1KDM4ETDP1 | |
| SCHEMBL6437412 | 0.84 | F7 (0.41) | TNNC1PPARATRPM2PDE5AALDH1A1 | |
| SCHEMBL10728796 | 0.83 | PTPN1 (0.58) | F7F3KDM4EALOX15HSD17B10 | |
| SCHEMBL10728792 | 0.83 | PTPN1 (0.58) | F7F3KDM4EALOX15HSD17B10 | |
| SCHEMBL11026071 | 0.82 | HDAC1 (0.43) | RARBTNNC1PPARATRPM2PDE5A | |
| SCHEMBL11026068 | 0.82 | HDAC1 (0.43) | RARBTNNC1PPARATRPM2PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673882-B2 | Inhibitors of autotaxin | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2014-03-18 | — | — | US | disclosed |
| US-20120190650-A1 | Inhibitors of Autotaxin | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2012-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190650-A1 | Inhibitors of Autotaxin | ENPP2, PHPT1, PSPH | RARB 3143/4885TNNC1 968/4885PPARA 3412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.