Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL890869 | 0.85 | KDM4E (0.54) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL29367451 | 0.85 | KDM4E (0.54) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11027702 | 0.80 | HRH1 (0.43) | SLC6A2SLC6A4HRH1LTA4HTSHR | |
| SCHEMBL11427361 | 0.80 | KDM4E (0.69) | HRH1LTA4HTSHRKDM4EMAPK1 | |
| SCHEMBL10437664 | 0.80 | KCNA3 (0.46) | SLC6A2SLC6A4HRH1LTA4HTSHR | |
| SCHEMBL10960140 | 0.80 | ALDH1A1 (0.63) | SLC6A2SLC6A4HRH1LTA4HTSHR | |
| SCHEMBL28300288 | 0.80 | LTA4H (0.55) | SLC6A2SLC6A4HRH1LTA4HTSHR | |
| SCHEMBL11028328 | 0.79 | LTA4H (0.64) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11210413 | 0.78 | ALDH1A1 (0.50) | HRH1LTA4HALDH1A1L3MBTL1RIPK1 | |
| SCHEMBL11522977 | 0.78 | KDM4E (0.55) | HRH1LTA4HKDM4EMAPK1KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071463-B1 | THIOLCARBAMATE COMPOUNDS, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-04-10 | — | — | EP | disclosed |
| US-4486449-A | INSECTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-12-04 | — | — | US | disclosed |
| EP-0071463-A1 | Thiolcarbamate compounds, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-02-09 | — | — | EP | disclosed |