Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
| ▸ | ESRRA | P11474 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1471670 | 0.86 | CYP1A2 (0.53) | CYP1A2CYP2C9CYP2C19MAPTLMNA | |
| SCHEMBL10962765 | 0.84 | MAPT (0.56) | CYP1A2CYP2C9CYP2C19MAPTLMNA | |
| SCHEMBL9171793 | 0.84 | CYP1A2 (0.64) | CYP1A2CYP2C9CYP2C19MAPTHSPB1 | |
| SCHEMBL11286995 | 0.84 | CYP1A2 (0.54) | CYP1A2CYP2C9CYP2C19MAPTLMNA | |
| SCHEMBL1472418 | 0.81 | TBXA2R (0.53) | CYP1A2CYP2C9CYP2C19MAPTLMNA | |
| SCHEMBL11028620 | 0.81 | MAPT (0.53) | CYP1A2CYP2C9CYP2C19MAPTLMNA | |
| SCHEMBL11029230 | 0.80 | MAPT (0.52) | CYP1A2CYP2C9CYP2C19MAPTLMNA | |
| SCHEMBL27675773 | 0.79 | CYP1A2 (0.53) | CYP1A2CYP2C9CYP2C19MAPTLMNA | |
| SCHEMBL27773191 | 0.78 | CYP1A2 (0.59) | CYP1A2CYP2C9CYP2C19MAPTLMNA | |
| SCHEMBL27886588 | 0.78 | CYP1A2 (0.53) | CYP1A2CYP2C9CYP2C19MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426385-A | Insecticidal bicyclooxyphenyl ureas | UNION CARBIDE CORPORATION (US) | 1984-01-17 | — | — | US | disclosed |
| EP-0050321-A2 | Novel bicyclooxyphenyl ureas, process for their preparation and pesticides containing them | UNION CARBIDE CORPORATION (US) | 1982-04-28 | — | — | EP | disclosed |