Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | PTGES | O14684 | 2/20 | 0.47 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9171793 | 0.85 | CYP1A2 (0.64) | CYP1A2CYP2C9CYP2C19HSPB1MEN1 | |
| SCHEMBL11028404 | 0.84 | CYP1A2 (0.53) | CYP1A2CYP2C9CYP2C19HSPB1MEN1 | |
| SCHEMBL1471670 | 0.82 | CYP1A2 (0.53) | CYP1A2CYP2C9CYP2C19HSPB1MEN1 | |
| SCHEMBL27886588 | 0.82 | CYP1A2 (0.53) | CYP1A2CYP2C9CYP2C19HSPB1MEN1 | |
| SCHEMBL27773191 | 0.82 | CYP1A2 (0.59) | CYP1A2CYP2C9CYP2C19HSPB1MEN1 | |
| SCHEMBL27713193 | 0.81 | HSPB1 (0.66) | ALOX5PTGESHSPB1MEN1KMT2A | |
| SCHEMBL11212598 | 0.81 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19HSPB1MEN1 | |
| SCHEMBL11030748 | 0.80 | ALOX5 (0.52) | CYP1A2CYP2C19ALOX5PTGESHSPB1 | |
| SCHEMBL6237528 | 0.80 | KMT2A (0.65) | CYP1A2CYP2C9CYP2C19ALOX5PTGES | |
| SCHEMBL27675773 | 0.80 | CYP1A2 (0.53) | CYP1A2CYP2C9CYP2C19HSPB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050321-A2 | Novel bicyclooxyphenyl ureas, process for their preparation and pesticides containing them | UNION CARBIDE CORPORATION (US) | 1982-04-28 | — | — | EP | disclosed |