Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | AKT1 | P31749 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | BCHE | P06276 | 3/20 | 0.53 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.53 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.53 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.48 |
| ▸ | RELA | Q04206 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033941 | 1.00 | RECQL (0.55) | RECQLAKT1MAPTLMNABCHE | |
| SCHEMBL2038400 | 0.80 | ALDH1A1 (0.41) | RECQLAKT1MAPTLMNABCHE | |
| SCHEMBL2954324 | 0.79 | MAPT (0.70) | RECQLAKT1MAPTLMNABCHE | |
| SCHEMBL11073619 | 0.79 | MAPT (0.70) | RECQLAKT1MAPTLMNABCHE | |
| SCHEMBL2954318 | 0.79 | MAPT (0.70) | RECQLAKT1MAPTLMNABCHE | |
| SCHEMBL28355230 | 0.79 | AKT1 (0.54) | RECQLAKT1MAPTLMNABCHE | |
| SCHEMBL26959426 | 0.79 | AKT1 (0.54) | RECQLAKT1MAPTLMNABCHE | |
| SCHEMBL11238958 | 0.79 | MAOB (0.59) | RECQLAKT1MAPTLMNABCHE | |
| SCHEMBL11008184 | 0.78 | ALDH1A1 (0.54) | RECQLAKT1MAPTLMNABCHE | |
| SCHEMBL16306951 | 0.78 | AKT1 (0.48) | RECQLAKT1MAPTLMNABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071165-B1 | UNSATURATED ARYL KETONES AS ANTISEBORRHOEIC ADDITIVES FOR COSMETIC COMPOSITIONS | Henkel Kommanditgesellschaft auf Aktien (DE) | 1985-09-04 | — | — | EP | disclosed |
| US-4439418-A | UNSATURATED ARYL KETONE | HENKEL KGAA (DE) | 1984-03-27 | — | — | US | disclosed |
| EP-0071165-A1 | Unsaturated aryl ketones as antiseborrhoeic additives for cosmetic compositions | Henkel Kommanditgesellschaft auf Aktien (DE) | 1983-02-09 | — | — | EP | disclosed |