Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4444755 | 0.80 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL16966565 | 0.76 | SRD5A1 (0.41) | ALDH1A1MAPTHPGDTDP1L3MBTL1 | |
| SCHEMBL11821006 | 0.72 | SRD5A1 (0.38) | ALDH1A1MAPTTDP1L3MBTL1KDM4E | |
| SCHEMBL29575333 | 0.72 | NPC1 (0.78) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL285733 | 0.72 | NPC1 (0.78) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3398506 | 0.71 | KDM4E (0.46) | SMN1; SMN2ALDH1A1MAPTTDP1KDM4E | |
| SCHEMBL6571738 | 0.71 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL28065049 | 0.71 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL4444701 | 0.70 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2228926 | 0.70 | NPC1 (0.71) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4611061-A | 2'-hydroxy-5'-(hydroxyalkyl)phenyl-2H-benzotriazoles | IOLAB CORPORATION (US) | 1986-09-09 | — | — | US | disclosed |