SCHEMBL285733

SCHEMBL285733

C=C(C)C(=O)Oc1ccc(C)cc1-n1nc2ccccc2n1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 9/20 0.78
RAB9A P51151 9/20 0.78
ALDH1A1 P00352 7/20 0.78
SMN1; SMN2 Q16637 6/20 0.78
MAPT P10636 7/20 0.62
KDM4E B2RXH2 7/20 0.62
HPGD P15428 6/20 0.62
TDP1 Q9NUW8 2/20 0.62
L3MBTL1 Q9Y468 2/20 0.61
NPSR1 Q6W5P4 1/20 0.61
POLB P06746 2/20 0.59
IGF2BP2 Q9Y6M1 1/20 0.56
THRB P10828 1/20 0.56
LMNA P02545 3/20 0.54
CYP1A2 P05177 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
ELANE P08246 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29575333 1.00 NPC1 (0.78) NPC1RAB9AALDH1A1SMN1; SMN2MAPT
SCHEMBL563078 0.88 NPC1 (1.00) NPC1RAB9AALDH1A1SMN1; SMN2MAPT
SCHEMBL29320693 0.88 NPC1 (0.64) NPC1RAB9AALDH1A1SMN1; SMN2MAPT
SCHEMBL29315815 0.87 NPC1 (0.63) NPC1RAB9AALDH1A1SMN1; SMN2MAPT
SCHEMBL29320728 0.85 NPC1 (0.60) NPC1RAB9AALDH1A1SMN1; SMN2MAPT
SCHEMBL29320726 0.85 NPC1 (0.60) NPC1RAB9AALDH1A1SMN1; SMN2MAPT
SCHEMBL29315811 0.85 NPC1 (0.60) NPC1RAB9AALDH1A1SMN1; SMN2MAPT
SCHEMBL4444701 0.85 NPC1 (0.56) NPC1RAB9AALDH1A1SMN1; SMN2MAPT
SCHEMBL29315791 0.85 KDM4E (0.60) NPC1RAB9AALDH1A1SMN1; SMN2MAPT
SCHEMBL29315789 0.84 KDM4E (0.59) NPC1RAB9AALDH1A1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 353 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12460088-B2 Omniphobic compositions with nanofiller additives, related articles, and related methods BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2025-11-04 US claimed
EP-3207076-B1 POLYMERS AND METHODS FOR OPTHALMIC APPLICATIONS KEY MEDICAL TECH INC (US) 2023-06-28 EP claimed
US-20230028815-A1 Omniphobic Composiitons with Nanofiller Additives, Related Articles, and Related Methods BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY 2023-01-26 US claimed
US-20220372322-A1 REVERSE PHOTOCHROMIC INKS INCLUDING ENCAPSULATED REVERSE PHOTOCHROMIC COLORANTS, AND ASSOCIATED METHODS AND WRITING INSTRUMENTS SANFORD LP (US) 2022-11-24 US claimed
US-20220242983-A1 POLYMERS AND METHODS FOR OPHTHALMIC APPLICATIONS KEY MEDICAL TECH INC (US) 2022-08-04 US claimed
US-20210324125-A1 POLYMERS AND METHODS FOR OPHTHALMIC APPLICATIONS KEY MEDICAL TECH INC (US) 2021-10-21 US claimed
WO-2021127229-A1 OMNIPHOBIC COMPOSITIONS WITH NANOFILLER ADDITIVES, RELATED ARTICLES, AND RELATED METHODS BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2021-06-24 WO claimed
WO-2021061769-A1 REVERSE PHOTOCHROMIC INKS INCLUDING ENCAPSULATED REVERSE PHOTOCHROMIC COLORANTS, AND ASSOCIATED METHODS AND WRITING INSTRUMENTS SANFORD L.P. (US) 2021-04-01 WO claimed
US-20200087433-A1 NANOHYBRID POLYMERS FOR OPHTHALMIC APPLICATIONS KEY MEDICAL TECH INC (US) 2020-03-19 US claimed
US-10463766-B2 Ultra violet, violet, and blue light filtering polymers for ophthalmic applications KEY MEDICAL TECHNOLOGIES, INC. (US) 2019-11-05 US claimed
US-6657029-B2 High refractive index monomer, greater amount of a hydrophilic monomer, crosslinker, and initiator; give water content; intraocular lenses BAUSCH & LOMB INCORPORATED 2003-12-02 US claimed
US-6657030-B2 High refractive index and hydrophilic monomers, a crosslinker, an initiator and water BAUSCH & LOMB INCORPORATED 2003-12-02 US claimed
US-20020049290-A1 High refractive index hydrogel compositions for ophthalmic implants VANDERBILT DAVID P (US) 2002-04-25 US claimed
US-20020042483-A1 High refractive index hydrogel compositions for ophthalmic implants VANDERBILT DAVID P (US) 2002-04-11 US claimed
US-20020042484-A1 High refractive index hydrogel compositions for ophthalmic implants BAUSCH & LOMB MEXICO, S.A. DE C.V. (MX) 2002-04-11 US claimed
US-20020037984-A1 High refractive index hydrogel compositions for ophthalmic implants VANDERBILT DAVID P (US) 2002-03-28 US claimed
US-6329485-B1 FOR INTRAOCULAR LENSES BAUSCH & LOMB INCORPORATED 2001-12-11 US claimed
WO-2000079312-A1 HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-12-28 WO claimed
WO-2000034804-A1 HIGH REFRACTIVE INDEX HYDROGEL COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-06-15 WO claimed
US-4260768-A Copolymerizable, ultraviolet light absorber 2-(2H-benzotriazol-2-yl)-4-alkylphenol acrylic acid esters GAF CORPORATION (US) 1981-04-07 US claimed