SCHEMBL11028673

SCHEMBL11028673

C1=CC2=C3OCCNC3CCCC2C=C1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL698710 0.90
SCHEMBL11360332 0.66
SCHEMBL4874913 0.65
SCHEMBL1866638 0.65
SCHEMBL30838391 0.64
SCHEMBL7831061 0.64
Hydrochloric Acid SCHEMBL10912090 0.64
SCHEMBL936883 0.63
SCHEMBL4131749 0.62
SCHEMBL7383347 0.60 DRD2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58092671-A None JP disclosed
EP-0080116-B1 OCTAHYDROBENZO(6,7)CYCLOHEPT(1,2-B)-1,4-OXAZINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL FORMULATION CONTAINING THEM MERCK & CO. INC. (US) 1986-12-10 EP disclosed
EP-0080116-A3 OCTAHYDROBENZO(6,7)CYCLOHEPT(1,2-B)-1,4-OXAZINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL FORMULATION CONTAINING THEM 1984-07-25 EP disclosed
JP-S5892671-A OCTAHYDROBENZO(6,7)CYCLOHEPT(1,2-B)-1,4-OXAZINES MERCK & CO INC 1983-06-02 JP disclosed
EP-0080116-A2 Octahydrobenzo(6,7)cyclohept(1,2-b)-1,4-oxazines, process for their preparation and pharmaceutical formulation containing them MERCK & CO. INC. (US) 1983-06-01 EP disclosed
US-4349548-A Octahydrobenzo[6,7]cyclohept[1,2-b]-1,4-oxazines, compositions and use MERCK & CO., INC. (US) 1982-09-14 US disclosed