Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11028739 | 1.00 | KDM4E (0.40) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11030317 | 0.90 | KMO (0.40) | ABL1CTSATRPV1 | |
| SCHEMBL11030321 | 0.90 | KMO (0.40) | ABL1CTSATRPV1 | |
| SCHEMBL11030238 | 0.88 | KDM4E (0.46) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11030232 | 0.88 | KDM4E (0.46) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29556312 | 0.86 | KDM4E (0.42) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16036061 | 0.86 | KDM4E (0.42) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29557179 | 0.82 | KDM4E (0.46) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16037442 | 0.82 | KDM4E (0.46) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11027603 | 0.81 | KDM4E (0.45) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658568-B2 | 6-amino-2-substituted-5-vinylsilylpyrimidine-4-carboxylic acids and esters and 4-amino-6-substituted-3-vinylsilylpyridine-2-carboxylic acids and esters as herbicides | DOW AGROSCIENCES, LLC. (US) | 2014-02-25 | — | — | US | disclosed |
| US-8658568-B2 | 6-amino-2-substituted-5-vinylsilylpyrimidine-4-carboxylic acids and esters and 4-amino-6-substituted-3-vinylsilylpyridine-2-carboxylic acids and esters as herbicides | DOW AGROSCIENCES, LLC. (US) | 2014-02-25 | — | — | US | disclosed |
| US-8658568-B2 | 6-amino-2-substituted-5-vinylsilylpyrimidine-4-carboxylic acids and esters and 4-amino-6-substituted-3-vinylsilylpyridine-2-carboxylic acids and esters as herbicides | DOW AGROSCIENCES, LLC. (US) | 2014-02-25 | — | — | US | disclosed |
| EP-2667717-A2 | 6-AMINO-2-SUBSTITUTED-5-VINYLSILYLPYRIMIDINE-4-CARBOXYLIC ACIDS AND ESTERS AND 4-AMINO-6-SUBSTITUTED-3-VINYLSILYLPYRIDINE-2-CARBOXYLIC ACIDS AND ESTERS AS HERBICIDES | Dow AgroSciences LLC (US) | 2013-12-04 | — | — | EP | disclosed |
| WO-2012103051-A2 | 6-AMINO-2-SUBSTITUTED-5-VINYLSILYLPYRIMIDINE-4-CARBOXYLIC ACIDS AND ESTERS AND 4-AMINO-6-SUBSTITUTED-3-VINYLSILYLPYRIDINE-2-CARBOXYLIC ACIDS AND ESTERS AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2012-08-02 | — | — | WO | disclosed |
| US-20120190549-A1 | 6-AMINO-2-SUBSTITUTED-5-VINYLSILYLPYRIMIDINE-4-CARBOXYLIC ACIDS AND ESTERS AND 4-AMINO-6-SUBSTITUTED-3-VINYLSILYLPYRIDINE-2-CARBOXYLIC ACIDS AND ESTERS AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190549-A1 | 6-AMINO-2-SUBSTITUTED-5-VINYLSILYLPYRIMIDINE-4-CARBOXYLIC ACIDS AND ESTERS AND 4-AMINO-6-SUBSTITUTED-3-VINYLSILYLPYRIDINE-2-CARBOXYLIC ACIDS AND ESTERS AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190549-A1 | 6-AMINO-2-SUBSTITUTED-5-VINYLSILYLPYRIMIDINE-4-CARBOXYLIC ACIDS AND ESTERS AND 4-AMINO-6-SUBSTITUTED-3-VINYLSILYLPYRIDINE-2-CARBOXYLIC ACIDS AND ESTERS AS HERBICIDES | DDT, PFAS, WEE2 | KDM4E 130/4885PKM 833/4885RCE1 2754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.