SCHEMBL11028795

SCHEMBL11028795

C=C(CCOC(=O)C(=C)CCC(C)OC(=O)C(=C)CCCCCCC)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
FAAH O00519 5/20 0.37
LMNA P02545 3/20 0.37
DGKA P23743 1/20 0.36
MAPT P10636 1/20 0.35
ALDH1A1 P00352 2/20 0.34
THRB P10828 1/20 0.34
FNTA P49354 1/20 0.34
FNTB P49356 1/20 0.34
PGGT1B P53609 1/20 0.34
CNR1 P21554 1/20 0.34
CNR2 P34972 1/20 0.34
FFAR4 Q5NUL3 1/20 0.33
PAM P19021 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11025964 0.92 LMNA (0.42) TSHRFAAHLMNAALDH1A1THRB
SCHEMBL11027815 0.87 TSHR (0.50) TSHRDGKAALDH1A1THRBFNTA
SCHEMBL11297340 0.84
SCHEMBL1299668 0.81 FAAH (0.50) FAAHLMNAMAPTALDH1A1CNR1
SCHEMBL17258179 0.81 FAAH (0.50) FAAHLMNAMAPTALDH1A1CNR1
SCHEMBL16208006 0.81 TSHR (0.44) TSHRDGKAALDH1A1THRBFNTA
SCHEMBL8773672 0.79 TSHR (0.51) TSHRDGKAALDH1A1THRBFNTA
SCHEMBL8009037 0.78 CAMK2A (0.31)
SCHEMBL20549641 0.77 TSHR (0.49) TSHRFAAHLMNADGKAMAPT
SCHEMBL17313431 0.77 TSHR (0.49) TSHRFAAHLMNADGKAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0059970-B1 EMBEDDING MEDIUM SUITABLE FOR THE PREPARATION OF THIN SECTIONS OF EMBEDDED BIOLOGICAL MATERIALS Chemische Werke Lowi GmbH (DE) 1985-07-24 EP claimed
US-4424329-A ALKYL AND/OR HYDROXYALKYL ACRYLATES, TRIETHYLENE GLYCOL DIMETHACRYLATE CHEMISCHE WERKE LOWI G.M.B.H. (DE) 1984-01-03 US claimed
EP-0059970-B1 EMBEDDING MEDIUM SUITABLE FOR THE PREPARATION OF THIN SECTIONS OF EMBEDDED BIOLOGICAL MATERIALS Chemische Werke Lowi GmbH (DE) 1985-07-24 EP disclosed
US-4424329-A ALKYL AND/OR HYDROXYALKYL ACRYLATES, TRIETHYLENE GLYCOL DIMETHACRYLATE CHEMISCHE WERKE LOWI G.M.B.H. (DE) 1984-01-03 US disclosed
US-4368312-A FOR STUDY UNDER A MICROSCOPE CHEMISCHE WERKE LOWI G.M.B.H. (DE) 1983-01-11 US disclosed