SCHEMBL11028811

SCHEMBL11028811

CCCc1ccccc1.CCc1ccccc1CC

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.52
GAA P10253 1/20 0.46
ALDH1A1 P00352 2/20 0.45
HTT P42858 1/20 0.45
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
CASP1 P29466 1/20 0.44
HSD17B10 Q99714 1/20 0.44
SIGMAR1 Q99720 2/20 0.44
CNR2 P34972 1/20 0.44
TAAR1 Q96RJ0 3/20 0.43
ATM Q13315 1/20 0.43
KEAP1 Q14145 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
CYP2A6 P11509 1/20 0.42
HTR2A P28223 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
LOXL2 Q9Y4K0 1/20 0.42
CHRM2 P08172 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Peroxide SCHEMBL10891803 0.98 TP53 (0.50) TP53GAAALDH1A1HTTHPGD
SCHEMBL3961595 0.96 TP53 (0.48) TP53GAAALDH1A1HTTHPGD
SCHEMBL40575 0.87
SCHEMBL11594885 0.87 TP53 (0.58) TP53ALDH1A1HPGDALOX15ALOX12
Benzene SCHEMBL3223041 0.87 TP53 (0.58) TP53ALDH1A1HPGDALOX15ALOX12
Benzene SCHEMBL28308118 0.87 TP53 (0.58) TP53ALDH1A1HPGDALOX15ALOX12
Butylbenzyl SCHEMBL27330531 0.86 ALDH1A1 (0.52) TP53ALDH1A1HPGDHSD17B10SIGMAR1
SCHEMBL3091432 0.86 HTT (0.53) TP53GAAALDH1A1HTTHPGD
SCHEMBL29540478 0.86 HTT (0.53) TP53GAAALDH1A1HTTHPGD
Ethylbenzene SCHEMBL9448399 0.85 TP53 (0.74) TP53ALDH1A1HPGDALOX15ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0085718-A4 SELECTIVELY CALCINED DEHYDROGENATION CATALYST. WILLIAMS DAVID L (US) 1984-01-10 EP disclosed
EP-0085718-A1 SELECTIVELY CALCINED DEHYDROGENATION CATALYST WILLIAMS, David L. (US) 1983-08-17 EP disclosed
WO-1983000687-A1 SELECTIVELY CALCINED DEHYDROGENATION CATALYST WILLIAMS, DAVID, L. 1983-03-03 WO disclosed