Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9440419 | 0.81 | SLC6A2 (0.44) | MRGPRX4ALDH1A1S1PR4NPC1RAB9A | |
| SCHEMBL4593423 | 0.81 | NOS2 (0.46) | MRGPRX4TDP1CYP2D6MAOAMAOB | |
| SCHEMBL11329798 | 0.81 | MAPT (0.53) | MRGPRX4TDP1TSHRALDH1A1HPGD | |
| SCHEMBL11026699 | 0.81 | KMT2A (0.47) | TDP1TSHRALDH1A1S1PR4HPGD | |
| SCHEMBL11031302 | 0.81 | MEN1 (0.48) | MRGPRX4TSHRALDH1A1HPGDNPC1 | |
| SCHEMBL11027469 | 0.81 | MAPT (0.50) | MRGPRX4TDP1ALDH1A1S1PR4HPGD | |
| SCHEMBL4033816 | 0.81 | CYP3A4 (0.42) | MRGPRX4TSHRALDH1A1CYP3A4 | |
| SCHEMBL29878016 | 0.81 | KMT2A (0.47) | TDP1TSHRALDH1A1S1PR4HPGD | |
| SCHEMBL3638624 | 0.81 | HPGD (0.58) | MRGPRX4TDP1TSHRALDH1A1S1PR4 | |
| SCHEMBL2641277 | 0.81 | TDP1 (0.56) | MRGPRX4TDP1TSHRS1PR4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022092687-A1 | COMPOSITION COMPRISING PROTEIN EXPRESSION INHIBITOR FOR ANTIOXIDATION, ANTIINFLAMMATION, AND DEMENTIA PREVENTION OR ALLEVIATION, AND USE THEREOF | 서울대학교산학협력단 | 2022-05-05 | — | — | WO | disclosed |
| WO-2021080188-A2 | COMPOSITION FOR PREVENTION OR TREATMENT OF DEPRESSION COMPRISING PROTEIN EXPRESSION INHIBITOR AND USE THEREOF | 서울대학교산학협력단 | 2021-04-29 | — | — | WO | disclosed |
| WO-2021080189-A1 | COMPOSITION FOR SKIN WHITENING, AND USE THEREOF | 서울대학교산학협력단 | 2021-04-29 | — | — | WO | disclosed |
| US-20200354327-A1 | COMPOUND HAVING STAT3 INHIBITORY ACTIVITY AND USE THEREOF | CYTUS H&B CO LTD (KR) | 2020-11-12 | — | — | US | disclosed |
| US-20200354327-A1 | COMPOUND HAVING STAT3 INHIBITORY ACTIVITY AND USE THEREOF | CYTUS H&B CO LTD (KR) | 2020-11-12 | — | — | US | disclosed |
| CN-111615509-A | Compound with signal transduction and transcriptional activator 3 inhibition activity and application thereof | 赛特思H&B有限公司 | 2020-09-01 | — | — | CN | disclosed |
| EP-0031938-B1 | USE OF ARYLOXY(THIO)CARBOXYLIC ACID NITRILES AND AMIDOXIMES AS ANTIDOTES AGAINST HERBICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-27 | — | — | EP | disclosed |
| US-4414020-A | AMIDOXIMES AS SAFENING AGENTS | HOECHST AG (DE) | 1983-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354327-A1 | COMPOUND HAVING STAT3 INHIBITORY ACTIVITY AND USE THEREOF | STAT3, JAK2, STAT6 | MRGPRX4 1849/4885TDP1 3889/4885TSHR 2574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.