SCHEMBL4593423

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1197763	0.82	MAPT (0.54)	NOS2MRGPRX4KDM4EMAPTTDP1
	SCHEMBL23677222	0.82	NOS2 (0.46)	NOS2MRGPRX4MAOAMAOBVCAM1
	SCHEMBL11028837	0.81	MRGPRX4 (0.53)	MRGPRX4MAOAMAOBTDP1CYP2D6
	Hydrochloric Acid SCHEMBL27743366	0.81	MAPT (0.52)	NOS2MRGPRX4KDM4EMAPTTDP1
	SCHEMBL6212985	0.79	XDH (0.60)	MRGPRX4MAOAMAOBXDHSLC6A4
	SCHEMBL11329798	0.79	MAPT (0.53)	MRGPRX4KDM4EMAPTTDP1CYP2D6
	SCHEMBL11031302	0.79	MEN1 (0.48)	MRGPRX4KDM4EMAPTSLC6A2SLC6A4
	SCHEMBL4918518	0.78	AR (0.47)	NOS2MRGPRX4MAOAMAOBKDM4E
	SCHEMBL7050401	0.78	MAOA (0.61)	NOS2MRGPRX4MAOAMAOBVCAM1
	SCHEMBL31441456	0.78	MAOA (0.61)	NOS2MRGPRX4MAOAMAOBVCAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.