Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14101249 | 0.77 | ALDH1A1 (0.37) | ALDH1A1MAPTKDM4EPOLBGAA | |
| SCHEMBL4274331 | 0.76 | MAPT (0.42) | MAPTESR1ESR2 | |
| SCHEMBL11625099 | 0.74 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL4271491 | 0.73 | CTSD (0.34) | — | |
| SCHEMBL3154825 | 0.71 | DUSP3 (0.34) | ALDH1A1MAPTKDM4EPOLBGAA | |
| SCHEMBL10454004 | 0.70 | ALDH1A1 (0.35) | ALDH1A1MAPTKDM4EPOLBGAA | |
| SCHEMBL11809693 | 0.70 | ALDH1A1 (0.31) | ALDH1A1MAPTPOLB | |
| SCHEMBL11814309 | 0.69 | — | — | |
| SCHEMBL10216432 | 0.68 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4EPOLBGAA | |
| SCHEMBL5710036 | 0.67 | MAPT (0.33) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090022047-A1 | OPTICAL RECORDING MEDIUM AND METHOD OF RECORDING VISIBLE INFORMATION | FUJIFILM CORPORATION (JP) | 2009-01-22 | — | — | US | disclosed |
| EP-0085158-B1 | PROCESS FOR THE PREPARATION OF CYCLOALKENON DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-06-19 | — | — | EP | disclosed |
| US-4465567-A | Process for the manufacture of 3-hydroxy-2-cycloalken-1-one derivatives | HOFFMANN-LA ROCHE INC. (US) | 1984-08-14 | — | — | US | disclosed |
| EP-0085158-A2 | Process for the preparation of cycloalkenon derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-08-10 | — | — | EP | disclosed |