Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11029999 | 0.88 | ALDH1A1 (0.33) | LMNATSHRTDP1 | |
| SCHEMBL13626989 | 0.58 | — | — | |
| SCHEMBL1473073 | 0.56 | — | — | |
| SCHEMBL7932752 | 0.56 | — | — | |
| Hydrochloric Acid SCHEMBL2412184 | 0.54 | — | — | |
| SCHEMBL5388758 | 0.54 | — | — | |
| SCHEMBL4635113 | 0.53 | LMNA (0.33) | LMNACYP1A2THRBBLMCREBBP | |
| SCHEMBL12039946 | 0.52 | HSP90AA1 (0.54) | LMNACYP1A2TDP1 | |
| SCHEMBL26180569 | 0.52 | TSHR (0.36) | TSHR | |
| SCHEMBL610419 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0078784-B1 | THIO-SUBSTITUTED-1,3,5-TRIAZINE-DIAMINES AND -TRIAMINES USEFUL AS PREVULCANIZATION INHIBITORS | MONSANTO COMPANY (US) | 1985-07-03 | — | — | EP | disclosed |
| US-4460769-A | Thio-amino-1,3,5-triazines | MONSANTO COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| EP-0078784-A1 | Thio-substituted-1,3,5-triazine-diamines and -triamines useful as prevulcanization inhibitors | MONSANTO COMPANY (US) | 1983-05-11 | — | — | EP | disclosed |
| US-4380609-A | Prevulcanization inhibitors of thio-triazine-amines for rubber | MONSANTO COMPANY (US) | 1983-04-19 | — | — | US | disclosed |
| US-4368196-A | INSECTICIDES, MITICIDES, OVICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1983-01-11 | — | — | US | disclosed |