Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11029563 | 0.90 | SLC29A1 (0.47) | SLC29A1ALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL11028065 | 0.90 | SLC29A1 (0.45) | SLC29A1ALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL11031534 | 0.86 | SLC29A1 (0.42) | SLC29A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11027412 | 0.85 | SLC29A1 (0.48) | SLC29A1ALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL11029641 | 0.84 | PDE4A (0.42) | SLC29A1SMN1; SMN2ALDH1A1MAPTPDE4A | |
| SCHEMBL11028323 | 0.84 | SLC29A1 (0.45) | SLC29A1SMN1; SMN2ALDH1A1MAPTPDE4A | |
| SCHEMBL10973367 | 0.82 | SMN1; SMN2 (0.33) | SMN1; SMN2NPSR1 | |
| SCHEMBL11049810 | 0.82 | PDE4A (0.40) | SLC29A1SMN1; SMN2ALDH1A1MAPTPDE4A | |
| SCHEMBL10971507 | 0.82 | CYP1A2 (0.37) | SLC29A1SMN1; SMN2ALDH1A1MAPTPDE4A | |
| SCHEMBL11049628 | 0.82 | SLC29A1 (0.43) | SLC29A1SMN1; SMN2MAPTPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055444-B1 | TRISUBSTITUTED PYRIMIDO(5,4-D)PYRIMIDINES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1985-03-20 | — | — | EP | disclosed |
| US-4478833-A | ANTICOAGULANTS | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-10-23 | — | — | US | disclosed |