SCHEMBL11029352

SCHEMBL11029352

O=C(O)c1n[nH]nc1C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.54
LMNA P02545 1/20 0.54
HAO1 Q9UJM8 2/20 0.44
HCAR2 Q8TDS4 10/20 0.41
LDHA P00338 1/20 0.40
LDHB P07195 1/20 0.40
KMT2A Q03164 1/20 0.38
TSHR P16473 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
HTT P42858 1/20 0.35
CYP2C19 P33261 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3033682 0.81
SCHEMBL22382 0.67 ALDH1A1 (0.55) KDM4EHCAR2LDHALDHBKMT2A
SCHEMBL28726114 0.65 ALDH1A1 (0.52) KDM4EHCAR2LDHALDHBKMT2A
SCHEMBL31279731 0.62 ALDH1A1 (0.50) KDM4EHCAR2LDHALDHBKMT2A
SCHEMBL2745093 0.62 ALDH1A1 (0.50) KDM4EHCAR2LDHALDHBKMT2A
SCHEMBL22027683 0.62 ALDH1A1 (0.38) KDM4ELMNAHCAR2LDHALDHB
SCHEMBL3482891 0.60 STAT5B (0.38) KDM4EHCAR2LDHALDHBKMT2A
SCHEMBL30807111 0.60 ALDH1A1 (0.48) KDM4EHCAR2LDHALDHBTSHR
SCHEMBL2804589 0.60 LDHA (0.46) KDM4EHCAR2LDHALDHBTSHR
SCHEMBL69939 0.60 KDM4E (0.54) KDM4ELMNAHCAR2KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8852320-B2 Preparation of metal-triazolate frameworks THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-10-07 US claimed
EP-2665733-A2 PREPARATION OF METAL-TRIAZOLATE FRAMEWORKS The Regents of The University of California (US) 2013-11-27 EP claimed
WO-2012100224-A2 PREPARATION OF METAL-TRIAZOLATE FRAMEWORKS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-07-26 WO claimed
US-20120186449-A1 PREPARATION OF METAL-TRIAZOLATE FRAMEWORKS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-07-26 US claimed
WO-2024230828-A1 COMPOUNDS, PREPARATION METHODS AND USES THEREOF InventisBio Co., Ltd. (CN) 2024-11-14 WO disclosed
EP-3241075-B1 STRIPPING COMPOSITIONS FOR REMOVING PHOTORESISTS FROM SEMICONDUCTOR SUBSTRATES FUJIFILM ELECTRONIC MAT USA INC (US) 2024-10-16 EP disclosed
CN-113637027-B Phenyl triazole dicarboxylic acid-rhodamine B derivative fluorescent probe and preparation method and application thereof 海南师范大学 2022-04-05 CN disclosed
CN-107850859-B Stripping composition for removing photoresist on semiconductor substrate 富士胶片电子材料美国有限公司 2021-06-01 CN disclosed
US-9914902-B2 Stripping compositions for removing photoresists from semiconductor substrates FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2018-03-13 US disclosed
EP-3241075-A1 STRIPPING COMPOSITIONS FOR REMOVING PHOTORESISTS FROM SEMICONDUCTOR SUBSTRATES FujiFilm Electronic Materials USA, Inc. (US) 2017-11-08 EP disclosed
US-20160186106-A1 STRIPPING COMPOSITIONS FOR REMOVING PHOTORESISTS FROM SEMICONDUCTOR SUBSTRATES FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2016-06-30 US disclosed
US-8852320-B2 Preparation of metal-triazolate frameworks THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-10-07 US disclosed
EP-2665733-A2 PREPARATION OF METAL-TRIAZOLATE FRAMEWORKS The Regents of The University of California (US) 2013-11-27 EP disclosed
US-20120186449-A1 PREPARATION OF METAL-TRIAZOLATE FRAMEWORKS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-07-26 US disclosed
WO-2012100224-A2 PREPARATION OF METAL-TRIAZOLATE FRAMEWORKS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-07-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120186449-A1 PREPARATION OF METAL-TRIAZOLATE FRAMEWORKS ILF3, SLC39A3, IKZF3 KDM4E 2616/4885LMNA 3770/4885HAO1 3121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.