Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 6/20 | 0.48 |
| ▸ | GCGR | P47871 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663041 | 0.91 | ALDH1A1 (0.48) | PYGLRAB9APOLBNPC1TDP1 | |
| SCHEMBL9133491 | 0.90 | PYGL (0.45) | PYGLGCGRRAB9APOLBNPC1 | |
| SCHEMBL9137528 | 0.88 | PYGL (0.53) | PYGLGCGRRAB9APOLBNPC1 | |
| SCHEMBL10959798 | 0.87 | GCGR (0.50) | PYGLGCGRRAB9APOLBNPC1 | |
| SCHEMBL10961383 | 0.86 | PYGL (0.51) | PYGLGCGRRAB9APOLBNPC1 | |
| SCHEMBL8657108 | 0.86 | PYGL (0.51) | PYGLGCGRRAB9APOLBNPC1 | |
| SCHEMBL8659524 | 0.85 | KMT2A (0.48) | PYGLRAB9APOLBNPC1IDO1 | |
| SCHEMBL8659841 | 0.85 | PYGL (0.52) | PYGLGCGRRAB9APOLBNPC1 | |
| SCHEMBL8656634 | 0.85 | PYGL (0.52) | PYGLGCGRRAB9APOLBNPC1 | |
| SCHEMBL10961025 | 0.85 | GCGR (0.51) | PYGLGCGRRAB9APOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426385-A | Insecticidal bicyclooxyphenyl ureas | UNION CARBIDE CORPORATION (US) | 1984-01-17 | — | — | US | claimed |
| EP-0050321-A2 | Novel bicyclooxyphenyl ureas, process for their preparation and pesticides containing them | UNION CARBIDE CORPORATION (US) | 1982-04-28 | — | — | EP | claimed |