Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL913495 | 0.86 | ANPEP (0.46) | ALDH1A1TSHRMAPK1ANPEPERAP2 | |
| SCHEMBL5862306 | 0.86 | ANPEP (0.46) | ALDH1A1TSHRMAPK1ANPEPERAP2 | |
| SCHEMBL24856 | 0.83 | — | — | |
| SCHEMBL12328671 | 0.81 | — | — | |
| SCHEMBL15374712 | 0.80 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL15400759 | 0.79 | ALDH1A1 (0.40) | ALDH1A1TSHR | |
| Phosphine SCHEMBL21380516 | 0.79 | ALDH1A1 (0.40) | ALDH1A1TSHR | |
| Water SCHEMBL20597605 | 0.79 | ALDH1A1 (0.40) | ALDH1A1TSHR | |
| SCHEMBL6577079 | 0.79 | ALDH1A1 (0.40) | ALDH1A1TSHR | |
| SCHEMBL10703282 | 0.79 | ALDH1A1 (0.40) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31587-E | Process for the preparation of 3-iminomethyl derivatives of rifamycin SV | ARCHIFAR LABORATORI CHIMICO FARMACOLOGICI S.P.A. (IT) | 1984-05-22 | — | — | US | disclosed |
| US-3963705-A | Process for the preparation of 3-iminomethyl derivatives of rifamycin SV | ARCHIFAR INDUSTRIE CHIMICHE DEL TRENTINO S.P.A. (IT) | 1976-06-15 | — | — | US | disclosed |