Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049931 | 0.92 | ACE (0.51) | ACECA1CA2 | |
| SCHEMBL11026152 | 0.92 | ACE (0.51) | ACECA1CA2 | |
| SCHEMBL11052803 | 0.88 | ACE (0.56) | ACELMNASMN1; SMN2ABCB11 | |
| SCHEMBL11050251 | 0.88 | ACE (0.56) | ACELMNASMN1; SMN2ABCB11 | |
| SCHEMBL11024516 | 0.86 | ACE (0.58) | ACELMNACA1CA2 | |
| Hydrochloric Acid SCHEMBL11030511 | 0.86 | ACE (0.57) | ACELMNACA1CA2 | |
| SCHEMBL11021929 | 0.84 | CA1 (0.56) | CA1CA2 | |
| SCHEMBL11021925 | 0.84 | CA1 (0.56) | CA1CA2 | |
| SCHEMBL11085040 | 0.83 | LMNA (0.43) | ACELMNASMN1; SMN2 | |
| SCHEMBL11050059 | 0.80 | ACE (0.52) | ACELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088350-B1 | CARBOXYALKYL DIPEPTIDES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1985-02-20 | — | — | EP | disclosed |
| US-4431644-A | CARDIOVASCULAR DISORDERS; DIURETICS | SCHERING CORPORATION (US) | 1984-02-14 | — | — | US | disclosed |
| EP-0088350-A1 | Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1983-09-14 | — | — | EP | disclosed |