Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.57 |
| ▸ | CA1 | P00915 | 4/20 | 0.57 |
| ▸ | CA2 | P00918 | 4/20 | 0.57 |
| ▸ | CA7 | P43166 | 4/20 | 0.57 |
| ▸ | CA9 | Q16790 | 4/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.57 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.57 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.57 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304475 | 0.81 | HSD17B10 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9305549 | 0.78 | THRA (0.49) | — | |
| SCHEMBL10745505 | 0.77 | KDM4E (0.55) | MEN1KMT2ANPC1CASP3SENP8 | |
| SCHEMBL10785616 | 0.77 | CA12 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10608463 | 0.75 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10722480 | 0.75 | SERPINE1 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4201347 | 0.75 | MAPT (0.71) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5710221 | 0.75 | MEN1 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30374772 | 0.75 | MEN1 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL21500819 | 0.74 | CA12 (0.53) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057503-B1 | PRODUCTION OF HYDROXY ARYLOPHENONES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-03-20 | — | — | EP | disclosed |
| US-4453010-A | Production of hydroxy arylophenones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-06-05 | — | — | US | disclosed |
| EP-0057503-A1 | Production of hydroxy arylophenones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-08-11 | — | — | EP | disclosed |