SCHEMBL9304475

SCHEMBL9304475

Cc1cccc(C)c1OC(=O)c1ccccc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 7/20 0.58
HPGD P15428 7/20 0.58
ALOX15 P16050 1/20 0.58
KMT2A Q03164 4/20 0.56
MEN1 O00255 3/20 0.56
ESR1 P03372 2/20 0.56
ESR2 Q92731 2/20 0.56
LMNA P02545 4/20 0.56
TSHR P16473 2/20 0.56
KDM4E B2RXH2 5/20 0.53
ALDH1A1 P00352 5/20 0.53
HTT P42858 2/20 0.47
NPC1 O15118 2/20 0.47
TP53 P04637 1/20 0.47
RAB9A P51151 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
MAPK1 P28482 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
TDP1 Q9NUW8 2/20 0.47
POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10745505 0.89 KDM4E (0.55) HSD17B10HPGDKMT2AMEN1ESR1
SCHEMBL29042646 0.86 HSD17B10 (0.54) HSD17B10HPGDALOX15KMT2AMEN1
SCHEMBL9678813 0.82 HPGD (0.54) HSD17B10HPGDALOX15KMT2AMEN1
SCHEMBL891120 0.82 HSD17B10 (0.67) HSD17B10HPGDALOX15KMT2AMEN1
SCHEMBL11029636 0.81 CA12 (0.57) KMT2AMEN1ESR1ESR2LMNA
SCHEMBL9851427 0.81 KMT2A (0.64) HSD17B10HPGDALOX15KMT2AMEN1
SCHEMBL11218323 0.81 HPGD (0.49) HSD17B10HPGDALOX15KMT2AMEN1
SCHEMBL11523328 0.81 ALDH1A1 (0.58) HSD17B10HPGDKMT2AMEN1ESR1
SCHEMBL8206089 0.79 HPGD (0.58) HSD17B10HPGDALOX15KMT2AMEN1
SCHEMBL8209348 0.79 HPGD (0.58) HSD17B10HPGDALOX15KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5319016-A Blend of vinyl polymer, modified polyolefin and hydrogenated vinyl-aliphatic diene block polymer in solvent CHISSO CORPORATION (JP) 1994-06-07 US disclosed
EP-0406828-B1 Emulsion adhesive composition and process for production thereof CHISSO CORP (JP) 1994-05-11 EP disclosed