Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | EEF2K | O00418 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6049469 | 0.80 | ALDH1A1 (0.47) | LMNATP53HTTEEF2KMEN1 | |
| SCHEMBL9214178 | 0.79 | LMNA (0.45) | LMNATP53HTTEEF2KMEN1 | |
| SCHEMBL11218472 | 0.77 | TDP1 (0.41) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL5729690 | 0.74 | MAPT (0.41) | LMNATP53HTTEEF2KMEN1 | |
| SCHEMBL11857458 | 0.71 | LMNA (0.49) | LMNATP53HTTCTSLALDH1A1 | |
| SCHEMBL9213048 | 0.70 | GAA (0.43) | LMNATP53HTTMEN1KMT2A | |
| SCHEMBL8749242 | 0.70 | GAA (0.43) | LMNATP53HTTMEN1KMT2A | |
| SCHEMBL17755077 | 0.69 | FFAR1 (0.56) | LMNATP53HTTEEF2KMEN1 | |
| SCHEMBL11820560 | 0.69 | TDP1 (0.44) | EEF2KMEN1KMT2AALDH1A1 | |
| SCHEMBL27671813 | 0.68 | LMNA (0.57) | LMNATP53HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4469688-A | INSECTICIDES, MITICIDES | UNION CARBIDE CORPORATION (US) | 1984-09-04 | — | — | US | disclosed |