Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.68 |
| ▸ | DRD2 | P14416 | 5/20 | 0.68 |
| ▸ | HTR7 | P34969 | 5/20 | 0.66 |
| ▸ | HTR1D | P28221 | 4/20 | 0.66 |
| ▸ | HTR1B | P28222 | 4/20 | 0.66 |
| ▸ | HTR2A | P28223 | 4/20 | 0.66 |
| ▸ | HTR2C | P28335 | 4/20 | 0.66 |
| ▸ | HTR2B | P41595 | 4/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.66 |
| ▸ | DRD3 | P35462 | 2/20 | 0.64 |
| ▸ | HTR5A | P47898 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11086815 | 1.00 | HTR1A (0.68) | HTR1ADRD2HTR7HTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL11089984 | 0.99 | HTR1A (0.67) | HTR1ADRD2HTR7HTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL11082872 | 0.99 | HTR1A (0.67) | HTR1ADRD2HTR7HTR1DHTR1B | |
| SCHEMBL11080260 | 0.99 | HTR1A (0.67) | HTR1ADRD2HTR7HTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL11083772 | 0.98 | HTR1A (0.66) | HTR1ADRD2HTR7HTR1DHTR1B | |
| SCHEMBL1491170 | 0.95 | DRD2 (0.67) | HTR1ADRD2HTR7HTR1DHTR1B | |
| Fumaric Acid SCHEMBL11088675 | 0.94 | HTR1A (0.61) | HTR1ADRD2HTR7HTR1DHTR1B | |
| Fumaric Acid SCHEMBL11088681 | 0.94 | HTR1A (0.61) | HTR1ADRD2HTR7HTR1DHTR1B | |
| SCHEMBL3068873 | 0.91 | HTR1A (0.68) | HTR1ADRD2DRD3 | |
| SCHEMBL11083371 | 0.90 | HTR1A (0.72) | HTR1ADRD2HTR7HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0074584-B1 | PROLONGED-ACTION MULTIPLE-LAYER TABLETS | Chugai Seiyaku Kabushiki Kaisha (JP) | 1985-08-21 | — | — | EP | claimed |
| US-4454108-A | Prolonged-action multiple-layer tablets | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1984-06-12 | — | — | US | claimed |
| JP-57004921-A | — | — | None | — | — | JP | disclosed |
| EP-0074584-B1 | PROLONGED-ACTION MULTIPLE-LAYER TABLETS | Chugai Seiyaku Kabushiki Kaisha (JP) | 1985-08-21 | — | — | EP | disclosed |
| US-4454108-A | Prolonged-action multiple-layer tablets | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1984-06-12 | — | — | US | disclosed |
| US-4438115-A | PIPERAZINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1984-03-20 | — | — | US | disclosed |
| EP-0042162-B1 | COMPOSITIONS FOR TREATING DISEASES IN CIRCULATORY ORGANS | Chugai Seiyaku Kabushiki Kaisha (JP) | 1983-11-23 | — | — | EP | disclosed |
| EP-0074584-A2 | Prolonged-action multiple-layer tablets | Chugai Seiyaku Kabushiki Kaisha (JP) | 1983-03-23 | — | — | EP | disclosed |
| JP-S574921-A | REMEDY FOR CARDIOVASCULAR DISORDER | CHUGAI PHARMACEUT CO LTD | 1982-01-11 | — | — | JP | disclosed |
| EP-0042162-A2 | Compositions for treating diseases in circulatory organs | Chugai Seiyaku Kabushiki Kaisha (JP) | 1981-12-23 | — | — | EP | disclosed |